Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | Lafayette (323) | 63 | 75 | Villanova (29) | Final | L | -12 |
| 2 | 2024-11-09 | Lafayette (323) | 60 | 81 | La Salle (237) | Final | L | -21 |
| 3 | 2024-11-12 | Penn (233) | 63 | 65 | Lafayette (231) | Final | W | 2 |
| 4 | 2024-11-16 | Lafayette (272) | 71 | 81 | Cornell (119) | Final | L | -10 |
| 5 | 2024-11-20 | Lafayette (323) | 72 | 86 | Rhode Island (145) | Final | L | -14 |
| 6 | 2024-11-24 | Rosemont | 45 | 91 | Lafayette (293) | Final | W | 46 |
| 7 | 2024-11-29 | Long Island (248) | 56 | 75 | Lafayette (236) | Final | W | 19 |
| 8 | 2024-11-30 | Niagara (337) | 47 | 59 | Lafayette (211) | Final | W | 12 |
| 9 | 2024-12-01 | Binghamton (332) | 82 | 81 | Lafayette (261) | Final (OT) | L | -1 |
| 10 | 2024-12-07 | Lafayette (230) | 77 | 73 | Mercyhurst (316) | Final | W | 4 |
| 11 | 2024-12-18 | Lafayette (246) | 62 | 82 | George Washington (102) | Final | L | -20 |
| 12 | 2024-12-21 | Lafayette (271) | 64 | 74 | Portland (310) | Final | L | -10 |
| 13 | 2024-12-29 | Stonehill (240) | 70 | 65 | Lafayette (283) | Final | L | -5 |
| 14 | 2025-01-02 | Boston University (265) | 46 | 60 | Lafayette (269) | Final | W | 14 |
| 15 | 2025-01-05 | Lafayette (281) | 70 | 71 | Navy (328) | Final | L | -1 |
| 16 | 2025-01-08 | Lafayette (289) | 62 | 65 | Bucknell (252) | Final (OT) | L | -3 |
| 17 | 2025-01-11 | Holy Cross (225) | 65 | 82 | Lafayette (279) | Final | W | 17 |
| 18 | 2025-01-15 | Lafayette (277) | 68 | 70 | Army (252) | Final | L | -2 |
| 19 | 2025-01-18 | Colgate (246) | 90 | 67 | Lafayette (300) | Final | L | -23 |
| 20 | 2025-01-22 | Lafayette (283) | 80 | 59 | Loyola-Maryland (288) | Final | W | 21 |
| 21 | 2025-01-25 | Lafayette (302) | 47 | 86 | Lehigh (294) | Final | L | -39 |
| 22 | 2025-01-29 | American (217) | 75 | 68 | Lafayette (305) | Final | L | -7 |
| 23 | 2025-02-01 | Lafayette (295) | 76 | 61 | Colgate (260) | Final | W | 15 |
| 24 | 2025-02-05 | Loyola-Maryland (289) | 71 | 58 | Lafayette (305) | Final | L | -13 |
| 25 | 2025-02-08 | Navy (323) | 51 | 61 | Lafayette (298) | Final | W | 10 |
| 26 | 2025-02-10 | Lafayette (302) | 58 | 60 | American (217) | Final | L | -2 |
| 27 | 2025-02-15 | Bucknell (236) | 75 | 69 | Lafayette (308) | Final | L | -6 |
| 28 | 2025-02-19 | Lafayette (313) | 69 | 74 | Holy Cross (282) | Final (OT) | L | -5 |
| 29 | 2025-02-22 | Lehigh (311) | 70 | 78 | Lafayette (308) | Final | W | 8 |
| 30 | 2025-02-25 | Army (339) | 65 | 81 | Lafayette (323) | Final | W | 16 |
| 31 | 2025-03-01 | Lafayette (323) | 64 | 66 | Boston University (267) | Final | L | -2 |
| 32 | 2025-03-04 | Holy Cross (310) | 68 | 69 | Lafayette (295) | Final | W | 1 |
| 33 | 2025-03-06 | Lafayette (297) | 69 | 71 | American (213) | Final | L | -2 |