Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | Fairleigh Dickinson (319) | 50 | 88 | Iowa State (19) | Final | W | 38 |
| 2 | 2025-11-06 | Grambling (336) | 62 | 102 | Iowa State (19) | Final | W | 40 |
| 3 | 2025-11-10 | Mississippi State (30) | 80 | 96 | Iowa State (19) | Final | W | 16 |
| 4 | 2025-11-17 | Stonehill | Iowa State | Scheduled – 7:00 PM | – | – | ||
| 5 | 2025-11-24 | St. John’s | Iowa State | Scheduled – 1:30 PM | – | – | ||
| 6 | 2025-11-25 | Iowa State | Creighton | Scheduled – 11:00 AM | – | – | ||
| 7 | 2025-12-03 | Alcorn State | Iowa State | Scheduled – 7:00 PM | – | – | ||
| 8 | 2025-12-06 | Iowa State | Purdue | Scheduled – 12:00 PM | – | – | ||
| 9 | 2025-12-11 | Iowa | Iowa State | Scheduled – 7:00 PM | – | – | ||
| 10 | 2025-12-14 | Eastern Illinois | Iowa State | Scheduled – 12:00 PM | – | – | ||
| 11 | 2025-12-21 | Long Beach State | Iowa State | Scheduled – 5:00 PM | – | – | ||
| 12 | 2025-12-29 | Houston Christian | Iowa State | Scheduled – 7:00 PM | – | – | ||
| 13 | 2026-01-02 | West Virginia | Iowa State | Scheduled – 8:00 PM | – | – | ||
| 14 | 2026-01-07 | Iowa State | Baylor | Scheduled – 7:00 PM | – | – | ||
| 15 | 2026-01-10 | Oklahoma State | Iowa State | Scheduled – 3:00 PM | – | – | ||
| 16 | 2026-01-13 | Iowa State | Kansas | Scheduled – 8:00 PM | – | – | ||
| 17 | 2026-01-17 | Iowa State | Cincinnati | Scheduled – 2:00 PM | – | – | ||
| 18 | 2026-01-20 | Central Florida | Iowa State | Scheduled – 6:00 PM | – | – | ||
| 19 | 2026-01-24 | Iowa State | Oklahoma State | Scheduled – 3:00 PM | – | – | ||
| 20 | 2026-01-29 | Colorado | Iowa State | Scheduled – 6:00 PM | – | – | ||
| 21 | 2026-02-01 | Iowa State | Kansas State | Scheduled – 1:00 PM | – | – | ||
| 22 | 2026-02-07 | Baylor | Iowa State | Scheduled – 1:00 PM | – | – | ||
| 23 | 2026-02-10 | Iowa State | TCU | Scheduled – 8:00 PM | – | – | ||
| 24 | 2026-02-14 | Kansas | Iowa State | Scheduled – 12:00 PM | – | – | ||
| 25 | 2026-02-16 | Houston | Iowa State | Scheduled – 8:00 PM | – | – | ||
| 26 | 2026-02-21 | Iowa State | BYU | Scheduled – 8:30 PM | – | – | ||
| 27 | 2026-02-24 | Iowa State | Utah | Scheduled – 7:00 PM | – | – | ||
| 28 | 2026-02-28 | Texas Tech | Iowa State | Scheduled – 3:00 PM | – | – | ||
| 29 | 2026-03-02 | Iowa State | Arizona | Scheduled – 7:00 PM | – | – | ||
| 30 | 2026-03-07 | Arizona State | Iowa State | Scheduled – 1:00 PM | – | – |