NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Samford (256) | 68 | 83 | Alabama (21) | Final | L | -15 |
| 2 | 2020-11-28 | Samford (256) | 64 | 66 | Auburn (81) | Final | L | -2 |
| 3 | 2020-12-03 | Samford (256) | 26 | 71 | Indiana (53) | Final | L | -45 |
| 4 | 2020-12-08 | Tennessee-Martin (249) | 75 | 67 | Samford (256) | Final | L | -8 |
| 5 | 2020-12-11 | North Alabama (340) | 66 | 79 | Samford (305) | Final | W | 13 |
| 6 | 2020-12-13 | Samford (256) | 54 | 88 | Kentucky (16) | Final | L | -34 |
| 7 | 2020-12-16 | Samford (256) | 46 | 63 | Jacksonville State (231) | Final | L | -17 |
| 8 | 2020-12-19 | Samford (256) | 0 | 0 | Tennessee Tech (222) | Cancelled | - | - |
| 9 | 2020-12-21 | Samford (256) | 0 | 0 | Western Kentucky (282) | Cancelled | - | - |
| 10 | 2020-12-28 | Samford (289) | 0 | 0 | Vanderbilt (71) | Cancelled | - | - |
| 11 | 2020-12-30 | Auburn-Montgomery | 0 | 0 | Samford (256) | Cancelled | - | - |
| 12 | 2020-12-31 | UA-Huntsville | 51 | 76 | Samford (256) | Final | W | 25 |
| 13 | 2021-01-04 | Birmingham-Southern | 60 | 135 | Samford (256) | Final | W | 75 |
| 14 | 2021-01-07 | Western Carolina (342) | Samford (242) | Cancelled | - | - | ||
| 15 | 2021-01-09 | UNC-Greensboro (349) | Samford (242) | Cancelled | - | - | ||
| 16 | 2021-01-09 | Mercer (245) | 69 | 78 | Samford (256) | Final | W | 9 |
| 17 | 2021-01-14 | Samford (186) | Chattanooga (154) | Cancelled | - | - | ||
| 18 | 2021-01-14 | Samford (186) | 84 | 49 | Western Carolina (316) | Final | W | 35 |
| 19 | 2021-01-16 | Samford (186) | East Tennessee State (286) | Cancelled | - | - | ||
| 20 | 2021-01-16 | Samford (256) | 64 | 47 | Western Carolina (353) | Final | W | 17 |
| 21 | 2021-01-21 | Samford (256) | 71 | 60 | Chattanooga (187) | Final | W | 11 |
| 22 | 2021-01-23 | Samford (169) | Mercer (128) | Cancelled | - | - | ||
| 23 | 2021-01-23 | Samford (256) | 57 | 70 | Chattanooga (187) | Final | L | -13 |
| 24 | 2021-01-28 | Wofford (189) | Samford (165) | Cancelled | - | - | ||
| 25 | 2021-01-28 | Furman (198) | 72 | 78 | Samford (256) | Final | W | 6 |
| 26 | 2021-01-30 | Furman (198) | 55 | 82 | Samford (256) | Final | W | 27 |
| 27 | 2021-02-04 | Samford (151) | UNC-Greensboro (323) | Cancelled | - | - | ||
| 28 | 2021-02-04 | UNC-Greensboro (254) | 42 | 46 | Samford (256) | Final | W | 4 |
| 29 | 2021-02-06 | Samford (151) | Western Carolina (307) | Cancelled | - | - | ||
| 30 | 2021-02-06 | UNC-Greensboro (254) | 44 | 70 | Samford (256) | Final | W | 26 |
| 31 | 2021-02-11 | East Tennessee State (319) | Samford (153) | Cancelled | - | - | ||
| 32 | 2021-02-11 | Samford (256) | 62 | 70 | Wofford (220) | Final | L | -8 |
| 33 | 2021-02-13 | Chattanooga (178) | Samford (153) | Cancelled | - | - | ||
| 34 | 2021-02-13 | Samford (256) | 80 | 55 | Wofford (220) | Final | W | 25 |
| 35 | 2021-02-18 | East Tennessee State (212) | 0 | 0 | Samford (256) | Cancelled | - | - |
| 36 | 2021-02-20 | Mercer (118) | Samford (153) | Cancelled | - | - | ||
| 37 | 2021-02-20 | East Tennessee State (212) | 58 | 77 | Samford (256) | Final | W | 19 |
| 38 | 2021-02-22 | Samford | UNC-Greensboro | Cancelled | - | - | ||
| 39 | 2021-02-25 | Samford (153) | Furman (254) | Cancelled | - | - | ||
| 40 | 2021-02-25 | Samford (256) | 74 | 65 | Mercer (245) | Final | W | 9 |
| 41 | 2021-02-27 | Samford (153) | Wofford (211) | Cancelled | - | - | ||
| 42 | 2021-03-04 | East Tennessee State (320) | 68 | 61 | Samford (140) | Final | L | -7 |
| 43 | 2021-03-19 | Samford (157) | 45 | 64 | Ole Miss (50) | Final | L | -19 |
| 44 | 2021-03-20 | Samford (157) | 62 | 68 | Illinois State (82) | Final | L | -6 |