NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-28 | East Tennessee State (212) | 62 | 56 | Longwood (171) | Final | W | 6 |
| 2 | 2020-12-01 | East Tennessee State (212) | 50 | 67 | Tennessee (33) | Final | L | -17 |
| 3 | 2020-12-08 | East Tennessee State (212) | 61 | 81 | Vanderbilt (7) | Final | L | -20 |
| 4 | 2020-12-12 | Presbyterian (357) | 68 | 38 | East Tennessee State (212) | Final | L | -30 |
| 5 | 2020-12-18 | East Tennessee State (212) | 64 | 70 | Davidson (79) | Final | L | -6 |
| 6 | 2020-12-20 | Appalachian State (153) | 69 | 66 | East Tennessee State (305) | Final | L | -3 |
| 7 | 2020-12-31 | Newberry | 55 | 69 | East Tennessee State (212) | Final | W | 14 |
| 8 | 2021-01-09 | East Tennessee State (212) | 51 | 66 | Chattanooga (187) | Final | L | -15 |
| 9 | 2021-01-14 | Mercer (117) | East Tennessee State (286) | Cancelled | - | - | ||
| 10 | 2021-01-14 | East Tennessee State (286) | 49 | 75 | Wofford (165) | Final | L | -26 |
| 11 | 2021-01-16 | Samford (186) | East Tennessee State (286) | Cancelled | - | - | ||
| 12 | 2021-01-16 | East Tennessee State (212) | 78 | 79 | Wofford (220) | Final/2OT | L | -1 |
| 13 | 2021-01-21 | East Tennessee State (301) | Furman (231) | Cancelled | - | - | ||
| 14 | 2021-01-22 | UNC-Greensboro (254) | 56 | 53 | East Tennessee State (212) | Final | L | -3 |
| 15 | 2021-01-23 | East Tennessee State (301) | Wofford (146) | Cancelled | - | - | ||
| 16 | 2021-01-24 | UNC-Greensboro (254) | 48 | 58 | East Tennessee State (212) | Final | W | 10 |
| 17 | 2021-01-28 | UNC-Greensboro (331) | East Tennessee State (308) | Cancelled | - | - | ||
| 18 | 2021-01-29 | Western Carolina (353) | 0 | 0 | East Tennessee State (212) | Cancelled | - | - |
| 19 | 2021-01-30 | Western Carolina (310) | East Tennessee State (308) | Cancelled | - | - | ||
| 20 | 2021-01-31 | Western Carolina (353) | 0 | 0 | East Tennessee State (212) | Postponed | - | - |
| 21 | 2021-02-05 | East Tennessee State (212) | 56 | 68 | Furman (198) | Final | L | -12 |
| 22 | 2021-02-06 | Chattanooga (174) | East Tennessee State (306) | Cancelled | - | - | ||
| 23 | 2021-02-07 | East Tennessee State (212) | 46 | 55 | Furman (198) | Final | L | -9 |
| 24 | 2021-02-11 | East Tennessee State (319) | Samford (153) | Cancelled | - | - | ||
| 25 | 2021-02-11 | Mercer (245) | 0 | 0 | East Tennessee State (212) | Cancelled | - | - |
| 26 | 2021-02-13 | East Tennessee State (319) | Mercer (118) | Cancelled | - | - | ||
| 27 | 2021-02-13 | Mercer (245) | 0 | 0 | East Tennessee State (212) | Postponed | - | - |
| 28 | 2021-02-18 | Wofford (211) | East Tennessee State (319) | Cancelled | - | - | ||
| 29 | 2021-02-18 | East Tennessee State (212) | 0 | 0 | Samford (256) | Cancelled | - | - |
| 30 | 2021-02-20 | Furman (254) | East Tennessee State (319) | Cancelled | - | - | ||
| 31 | 2021-02-20 | East Tennessee State (212) | 58 | 77 | Samford (256) | Final | L | -19 |
| 32 | 2021-02-23 | Western Carolina (319) | 62 | 48 | East Tennessee State (315) | Final | L | -14 |
| 33 | 2021-02-25 | East Tennessee State (319) | Western Carolina (308) | Cancelled | - | - | ||
| 34 | 2021-02-25 | Chattanooga (187) | 65 | 54 | East Tennessee State (212) | Final | L | -11 |
| 35 | 2021-02-27 | East Tennessee State (319) | UNC-Greensboro (326) | Cancelled | - | - | ||
| 36 | 2021-02-27 | Mercer (245) | 76 | 73 | East Tennessee State (212) | Final | L | -3 |
| 37 | 2021-03-04 | East Tennessee State (320) | 68 | 61 | Samford (140) | Final | W | 7 |
| 38 | 2021-03-05 | East Tennessee State (212) | 64 | 75 | Wofford (220) | Final | L | -11 |