NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | SIU-Edwardsville (242) | 66 | 50 | Purdue Fort Wayne (148) | Final | L | -16 |
| 2 | 2020-12-05 | Purdue Fort Wayne (148) | 60 | 70 | Evansville (272) | Final | L | -10 |
| 3 | 2020-12-12 | Purdue Fort Wayne (148) | 36 | 75 | IU-Indy (247) | Final | L | -39 |
| 4 | 2020-12-13 | Purdue Fort Wayne (148) | 59 | 80 | IU-Indy (247) | Final | L | -21 |
| 5 | 2020-12-19 | Northern Kentucky (193) | 83 | 48 | Purdue Fort Wayne (148) | Final | L | -35 |
| 6 | 2020-12-20 | Northern Kentucky (267) | 80 | 63 | Purdue Fort Wayne (348) | Final | L | -17 |
| 7 | 2021-01-01 | Illinois-Chicago (312) | Purdue Fort Wayne (349) | Cancelled | - | - | ||
| 8 | 2021-01-01 | Cleveland State (133) | 85 | 51 | Purdue Fort Wayne (148) | Final | L | -34 |
| 9 | 2021-01-02 | Illinois-Chicago (312) | Purdue Fort Wayne (349) | Cancelled | - | - | ||
| 10 | 2021-01-02 | Cleveland State (133) | 72 | 57 | Purdue Fort Wayne (148) | Final | L | -15 |
| 11 | 2021-01-08 | Purdue Fort Wayne (148) | 42 | 62 | Milwaukee (318) | Final | L | -20 |
| 12 | 2021-01-09 | Purdue Fort Wayne (148) | 33 | 64 | Milwaukee (318) | Final | L | -31 |
| 13 | 2021-01-15 | Green Bay (89) | 62 | 46 | Purdue Fort Wayne (148) | Final | L | -16 |
| 14 | 2021-01-16 | Green Bay (89) | 70 | 59 | Purdue Fort Wayne (148) | Final | L | -11 |
| 15 | 2021-01-22 | Purdue Fort Wayne (148) | 49 | 58 | Oakland (262) | Final | L | -9 |
| 16 | 2021-01-23 | Purdue Fort Wayne (148) | 61 | 73 | Oakland (262) | Final | L | -12 |
| 17 | 2021-01-29 | Detroit (329) | Purdue Fort Wayne (341) | Cancelled | - | - | ||
| 18 | 2021-01-29 | Wright State (299) | 77 | 50 | Purdue Fort Wayne (148) | Final | L | -27 |
| 19 | 2021-01-30 | Detroit (329) | Purdue Fort Wayne (341) | Cancelled | - | - | ||
| 20 | 2021-01-30 | Wright State (299) | 69 | 59 | Purdue Fort Wayne (148) | Final | L | -10 |
| 21 | 2021-02-05 | Purdue Fort Wayne (148) | 60 | 102 | Youngstown State (124) | Final | L | -42 |
| 22 | 2021-02-06 | Purdue Fort Wayne (148) | 52 | 68 | Youngstown State (124) | Final | L | -16 |
| 23 | 2021-02-12 | Purdue Fort Wayne (148) | 45 | 68 | Cleveland State (133) | Final | L | -23 |
| 24 | 2021-02-13 | Purdue Fort Wayne (148) | 61 | 71 | Cleveland State (133) | Final | L | -10 |
| 25 | 2021-02-19 | Robert Morris (215) | 67 | 71 | Purdue Fort Wayne (148) | Final | W | 4 |
| 26 | 2021-02-20 | Robert Morris (215) | 77 | 63 | Purdue Fort Wayne (148) | Final | L | -14 |
| 27 | 2021-02-25 | Purdue Fort Wayne (148) | 59 | 62 | Youngstown State (124) | Final | L | -3 |