NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Nicholls State (273) | 43 | 88 | Tulane (211) | Final | L | -45 |
| 2 | 2020-12-02 | Mobile | 53 | 81 | Nicholls State (273) | Final | W | 28 |
| 3 | 2020-12-05 | Nicholls State (273) | 66 | 74 | South Alabama (194) | Final | L | -8 |
| 4 | 2020-12-08 | Nicholls State (273) | 0 | 0 | Southern Miss (197) | Cancelled | - | - |
| 5 | 2020-12-11 | Jackson State (315) | 75 | 60 | Nicholls State (316) | Final | L | -15 |
| 6 | 2020-12-12 | Jackson State (314) | 0 | 0 | Nicholls State (273) | Cancelled | - | - |
| 7 | 2020-12-16 | Nicholls State (273) | 46 | 86 | Alabama (21) | Final | L | -40 |
| 8 | 2020-12-18 | Nicholls State (273) | 50 | 63 | Southern Miss (197) | Final | L | -13 |
| 9 | 2020-12-30 | Nicholls State (273) | 61 | 67 | Alabama A&M (196) | Final | L | -6 |
| 10 | 2021-01-02 | Sam Houston State (162) | 82 | 89 | Nicholls State (273) | Final | W | 7 |
| 11 | 2021-01-06 | Nicholls State (273) | 40 | 66 | Lamar (186) | Final | L | -26 |
| 12 | 2021-01-09 | Southeastern Louisiana (349) | 63 | 76 | Nicholls State (273) | Final | W | 13 |
| 13 | 2021-01-13 | Northwestern State (343) | 38 | 68 | Nicholls State (293) | Final | W | 30 |
| 14 | 2021-01-16 | Nicholls State (273) | 42 | 56 | Central Arkansas (131) | Final | L | -14 |
| 15 | 2021-01-20 | Houston Christian (328) | 0 | 0 | Nicholls State (273) | Postponed | - | - |
| 16 | 2021-01-23 | New Orleans (356) | 56 | 67 | Nicholls State (273) | Final | W | 11 |
| 17 | 2021-01-27 | Nicholls State (273) | 63 | 43 | McNeese (80) | Final | W | 20 |
| 18 | 2021-01-30 | Nicholls State (273) | 61 | 70 | Houston Christian (328) | Final | L | -9 |
| 19 | 2021-02-06 | Nicholls State (273) | 58 | 72 | Sam Houston State (162) | Final | L | -14 |
| 20 | 2021-02-10 | Lamar (241) | 77 | 79 | Nicholls State (276) | Final/OT | W | 2 |
| 21 | 2021-02-13 | Nicholls State (273) | 63 | 82 | Southeastern Louisiana (349) | Final | L | -19 |
| 22 | 2021-02-17 | Nicholls State (273) | 0 | 0 | Northwestern State (214) | Postponed | - | - |
| 23 | 2021-02-20 | Central Arkansas (131) | 61 | 50 | Nicholls State (273) | Final | L | -11 |
| 24 | 2021-02-22 | Nicholls State (273) | 72 | 65 | Northwestern State (214) | Final | W | 7 |
| 25 | 2021-02-24 | Houston Christian (328) | 64 | 59 | Nicholls State (273) | Final | L | -5 |
| 26 | 2021-02-27 | Nicholls State (273) | 66 | 59 | New Orleans (356) | Final | W | 7 |
| 27 | 2021-03-03 | McNeese (80) | 68 | 71 | Nicholls State (273) | Final | W | 3 |
| 28 | 2021-03-11 | Abilene Christian (190) | 57 | 67 | Nicholls State (283) | Final | W | 10 |
| 29 | 2021-03-12 | Nicholls State (283) | 59 | 89 | Sam Houston State (157) | Final | L | -30 |