NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-28 | Loyola-Chicago (175) | 70 | 57 | Chicago State (346) | Final | W | 13 |
| 2 | 2020-12-13 | Loyola-Chicago (175) | 67 | 76 | DePaul (229) | Final | L | -9 |
| 3 | 2020-12-18 | Loyola-Chicago (219) | Western Michigan (263) | Cancelled | - | - | ||
| 4 | 2020-12-18 | Purdue Northwest | 61 | 80 | Loyola-Chicago (175) | Final | W | 19 |
| 5 | 2020-12-21 | Central Michigan (128) | 73 | 64 | Loyola-Chicago (175) | Final | L | -9 |
| 6 | 2021-01-01 | Indiana State (285) | 63 | 48 | Loyola-Chicago (175) | Final | L | -15 |
| 7 | 2021-01-02 | Loyola-Chicago (228) | Valparaiso (115) | Cancelled | - | - | ||
| 8 | 2021-01-02 | Indiana State (285) | 52 | 59 | Loyola-Chicago (175) | Final | W | 7 |
| 9 | 2021-01-07 | Loyola-Chicago (213) | Drake (146) | Cancelled | - | - | ||
| 10 | 2021-01-08 | Loyola-Chicago (175) | 0 | 0 | Missouri State (110) | Postponed | - | - |
| 11 | 2021-01-09 | Loyola-Chicago (213) | Northern Iowa (71) | Cancelled | - | - | ||
| 12 | 2021-01-09 | Loyola-Chicago (175) | 0 | 0 | Missouri State (110) | Postponed | - | - |
| 13 | 2021-01-15 | Southern Illinois (158) | Loyola-Chicago (201) | Cancelled | - | - | ||
| 14 | 2021-01-17 | Missouri State (31) | Loyola-Chicago (201) | Cancelled | - | - | ||
| 15 | 2021-01-19 | Loyola-Chicago (175) | 53 | 36 | Valparaiso (360) | Final | W | 17 |
| 16 | 2021-01-22 | Loyola-Chicago (227) | Indiana State (255) | Cancelled | - | - | ||
| 17 | 2021-01-22 | Loyola-Chicago (175) | 71 | 66 | Bradley (155) | Final | W | 5 |
| 18 | 2021-01-23 | Loyola-Chicago (175) | 55 | 57 | Bradley (155) | Final | L | -2 |
| 19 | 2021-01-24 | Loyola-Chicago (227) | Evansville (292) | Cancelled | - | - | ||
| 20 | 2021-01-29 | Illinois State (110) | Loyola-Chicago (175) | Cancelled | - | - | ||
| 21 | 2021-01-30 | Southern Illinois (291) | 46 | 53 | Loyola-Chicago (175) | Final | W | 7 |
| 22 | 2021-01-31 | Bradley (93) | Loyola-Chicago (175) | Cancelled | - | - | ||
| 23 | 2021-01-31 | Southern Illinois (291) | 46 | 55 | Loyola-Chicago (175) | Final | W | 9 |
| 24 | 2021-02-05 | Northern Iowa (96) | Loyola-Chicago (144) | Cancelled | - | - | ||
| 25 | 2021-02-05 | Drake (236) | 75 | 46 | Loyola-Chicago (175) | Final | L | -29 |
| 26 | 2021-02-06 | Drake (236) | 68 | 64 | Loyola-Chicago (175) | Final | L | -4 |
| 27 | 2021-02-07 | Drake (89) | Loyola-Chicago (144) | Cancelled | - | - | ||
| 28 | 2021-02-12 | Loyola-Chicago (166) | Missouri State (21) | Cancelled | - | - | ||
| 29 | 2021-02-12 | Loyola-Chicago (175) | 67 | 49 | Evansville (272) | Final | W | 18 |
| 30 | 2021-02-13 | Loyola-Chicago (175) | 61 | 31 | Evansville (272) | Final | W | 30 |
| 31 | 2021-02-14 | Loyola-Chicago (166) | Southern Illinois (176) | Cancelled | - | - | ||
| 32 | 2021-02-18 | Evansville (271) | Loyola-Chicago (166) | Cancelled | - | - | ||
| 33 | 2021-02-19 | Loyola-Chicago (175) | 51 | 78 | Northern Iowa (132) | Final | L | -27 |
| 34 | 2021-02-20 | Indiana State (269) | Loyola-Chicago (166) | Cancelled | - | - | ||
| 35 | 2021-02-20 | Loyola-Chicago (175) | 66 | 64 | Northern Iowa (132) | Final/OT | W | 2 |
| 36 | 2021-02-24 | Valparaiso (360) | 57 | 55 | Loyola-Chicago (175) | Final | L | -2 |
| 37 | 2021-02-26 | Loyola-Chicago (166) | Bradley (102) | Cancelled | - | - | ||
| 38 | 2021-02-27 | Loyola-Chicago (175) | 50 | 64 | Missouri State (110) | Final | L | -14 |
| 39 | 2021-02-28 | Loyola-Chicago (166) | Illinois State (107) | Cancelled | - | - | ||
| 40 | 2021-02-28 | Loyola-Chicago (175) | 45 | 59 | Missouri State (110) | Final | L | -14 |
| 41 | 2021-03-04 | Valparaiso (158) | Loyola-Chicago (166) | Cancelled | - | - | ||
| 42 | 2021-03-05 | Illinois State (136) | 64 | 61 | Loyola-Chicago (175) | Final | L | -3 |
| 43 | 2021-03-06 | Illinois State (136) | 60 | 45 | Loyola-Chicago (175) | Final | L | -15 |
| 44 | 2021-03-12 | Loyola-Chicago (167) | 61 | 60 | Illinois State (74) | Final | W | 1 |
| 45 | 2021-03-13 | Loyola-Chicago (167) | 0 | 0 | Drake (71) | Cancelled | - | - |
| 46 | 2021-03-13 | Loyola-Chicago (175) | 56 | 70 | Bradley (155) | Final | L | -14 |