NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Houston (180) | 97 | 85 | Oklahoma (10) | Final | W | 12 |
| 2 | 2020-11-28 | Jackson State (180) | Houston (176) | Cancelled | - | - | ||
| 3 | 2020-11-29 | Houston (180) | 66 | 88 | Alabama (21) | Final | L | -22 |
| 4 | 2020-12-05 | Auburn (81) | 61 | 71 | Houston (180) | Final | W | 10 |
| 5 | 2020-12-08 | Houston (129) | Texas-Arlington (125) | Cancelled | - | - | ||
| 6 | 2020-12-11 | Stephen F. Austin (56) | 59 | 61 | Houston (57) | Final | W | 2 |
| 7 | 2020-12-16 | Cincinnati (122) | 0 | 0 | Houston (180) | Postponed | - | - |
| 8 | 2020-12-19 | Houston (180) | 0 | 0 | South Florida (72) | Postponed | - | - |
| 9 | 2020-12-22 | Houston (180) | 75 | 63 | Memphis (239) | Final | W | 12 |
| 10 | 2020-12-30 | Wichita State (266) | 65 | 79 | Houston (180) | Final | W | 14 |
| 11 | 2021-01-03 | Houston (180) | 46 | 55 | Central Florida (150) | Final | L | -9 |
| 12 | 2021-01-06 | Tulane (211) | 76 | 62 | Houston (180) | Final | L | -14 |
| 13 | 2021-01-09 | Houston (57) | SMU (312) | Cancelled | - | - | ||
| 14 | 2021-01-09 | Houston (180) | 51 | 80 | South Florida (72) | Final | L | -29 |
| 15 | 2021-01-13 | Tulsa (112) | 49 | 75 | Houston (82) | Final | W | 26 |
| 16 | 2021-01-16 | Houston (180) | 66 | 56 | East Carolina (106) | Final | W | 10 |
| 17 | 2021-01-20 | Temple (151) | 46 | 80 | Houston (180) | Final | W | 34 |
| 18 | 2021-01-23 | Central Florida (150) | 50 | 38 | Houston (180) | Final | L | -12 |
| 19 | 2021-01-27 | Houston (180) | 71 | 64 | Tulane (211) | Final | W | 7 |
| 20 | 2021-01-30 | SMU (209) | 0 | 0 | Houston (180) | Cancelled | - | - |
| 21 | 2021-02-03 | Houston (180) | 64 | 56 | Tulsa (140) | Final | W | 8 |
| 22 | 2021-02-10 | Houston (46) | 89 | 52 | Temple (126) | Final | W | 37 |
| 23 | 2021-02-13 | Memphis (239) | 50 | 71 | Houston (180) | Final | W | 21 |
| 24 | 2021-02-17 | East Carolina (106) | 0 | 0 | Houston (180) | Cancelled | - | - |
| 25 | 2021-02-20 | Houston (180) | 75 | 66 | Cincinnati (122) | Final | W | 9 |
| 26 | 2021-02-24 | Houston (180) | 77 | 65 | Wichita State (266) | Final | W | 12 |
| 27 | 2021-02-27 | South Florida (72) | 49 | 67 | Houston (180) | Final | W | 18 |
| 28 | 2021-03-02 | Cincinnati (122) | 65 | 57 | Houston (180) | Final | L | -8 |
| 29 | 2021-03-09 | East Carolina (172) | 63 | 73 | Houston (42) | Final | W | 10 |
| 30 | 2021-03-10 | Houston (42) | 39 | 61 | Central Florida (24) | Final | L | -22 |
| 31 | 2021-03-19 | San Francisco (109) | 71 | 63 | Houston (42) | Final | L | -8 |
| 32 | 2021-03-20 | Houston (42) | 0 | 0 | New Mexico (70) | Cancelled | - | - |
| 33 | 2021-03-22 | Houston (42) | 50 | 48 | Arizona State (85) | Final | W | 2 |