NCAA Women’s Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-29 | North Alabama (115) | 69 | 80 | Purdue (41) | Final | W | 11 |
| 2 | 2020-12-03 | Miami (OH) (311) | 0 | 0 | Purdue (101) | Canceled | – | – |
| 3 | 2020-12-06 | Valparaiso (277) | 52 | 47 | Purdue (101) | Final | L | -5 |
| 4 | 2020-12-09 | Buffalo (83) | 70 | 82 | Purdue (220) | Final | W | 12 |
| 5 | 2020-12-13 | Bowling Green (18) | 73 | 79 | Purdue (220) | Final | W | 6 |
| 6 | 2020-12-17 | Northwestern (48) | 70 | 54 | Purdue (55) | Final | L | -16 |
| 7 | 2020-12-20 | Purdue (55) | 91 | 87 | Penn State (63) | Final | W | 4 |
| 8 | 2020-12-23 | Nebraska (116) | 72 | 83 | Purdue (67) | Final | W | 11 |
| 9 | 2021-01-03 | Michigan State (13) | 71 | 64 | Purdue (56) | Final | L | -7 |
| 10 | 2021-01-07 | Purdue (63) | 0 | 0 | Rutgers (60) | Postponed | – | – |
| 11 | 2021-01-10 | Purdue (63) | 46 | 83 | Maryland (11) | Final | L | -37 |
| 12 | 2021-01-14 | Indiana (24) | 66 | 45 | Purdue (75) | Final | L | -21 |
| 13 | 2021-01-18 | Purdue (75) | 81 | 87 | Iowa (34) | Final | L | -6 |
| 14 | 2021-01-21 | Wisconsin (186) | 55 | 56 | Purdue (84) | Final | W | 1 |
| 15 | 2021-01-24 | Purdue (84) | 0 | 0 | Michigan (6) | Postponed | – | – |
| 16 | 2021-01-28 | Purdue (84) | 72 | 77 | Minnesota (142) | Final | L | -5 |
| 17 | 2021-01-31 | Penn State (113) | 80 | 70 | Purdue (84) | Final | L | -10 |
| 18 | 2021-02-07 | Purdue (106) | 49 | 54 | Illinois (235) | Final | L | -5 |
| 19 | 2021-02-11 | Michigan (13) | 62 | 49 | Purdue (122) | Final | L | -13 |
| 20 | 2021-02-14 | Rutgers (47) | 75 | 57 | Purdue (122) | Final | L | -18 |
| 21 | 2021-02-18 | Purdue (132) | 85 | 100 | Ohio State (21) | Final | L | -15 |
| 22 | 2021-02-21 | Purdue (132) | 73 | 76 | Michigan State (41) | Final | L | -3 |
| 23 | 2021-02-25 | Maryland (8) | 88 | 59 | Purdue (144) | Final | L | -29 |
| 24 | 2021-02-28 | Illinois (231) | 66 | 70 | Purdue (144) | Final | W | 4 |
| 25 | 2021-03-06 | Purdue (134) | 59 | 74 | Indiana (12) | Final | L | -15 |
| 26 | 2021-03-10 | Purdue (133) | 72 | 83 | Iowa (36) | Final | L | -11 |