Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Kent State (89) | 20 | Washington (108) | 45 | Final | W | 25 |
| 2 | 2022-09-10 | Portland State (179) | 6 | Washington (108) | 52 | Final | W | 46 |
| 3 | 2022-09-17 | Michigan State (36) | 28 | Washington (9) | 39 | Final | W | 11 |
| 4 | 2022-09-24 | Stanford (79) | 22 | Washington (12) | 40 | Final | W | 18 |
| 5 | 2022-09-30 | Washington (24) | 32 | UCLA (9) | 40 | Final | L | -8 |
| 6 | 2022-10-08 | Washington (48) | 38 | Arizona State (84) | 45 | Final | L | -7 |
| 7 | 2022-10-15 | Arizona (91) | 39 | Washington (36) | 49 | Final | W | 10 |
| 8 | 2022-10-22 | Washington (33) | 28 | California (94) | 21 | Final | W | 7 |
| 9 | 2022-11-04 | Oregon State (32) | 21 | Washington (26) | 24 | Final | W | 3 |
| 10 | 2022-11-12 | Washington (21) | 37 | Oregon (12) | 34 | Final | W | 3 |
| 11 | 2022-11-19 | Colorado (133) | 7 | Washington (17) | 54 | Final | W | 47 |
| 12 | 2022-11-26 | Washington (16) | 51 | Washington State (43) | 33 | Final | W | 18 |
| 13 | 2022-12-29 | Texas (11) | 20 | Washington (16) | 27 | Final | W | 7 |