Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-09-02 | Western Michigan | 31 | USC | 49 | Final | W | 18 |
| 2 | 2017-09-09 | Stanford (16) | 24 | USC (10) | 42 | Final | W | 18 |
| 3 | 2017-09-16 | Texas (73) | 24 | USC (10) | 27 | Final/2OT | W | 3 |
| 4 | 2017-09-23 | USC | 30 | California | 20 | Final | W | 10 |
| 5 | 2017-09-29 | USC | 27 | Washington State | 30 | Final | L | -3 |
| 6 | 2017-10-07 | Oregon State (98) | 10 | USC (11) | 38 | Final | W | 28 |
| 7 | 2017-10-14 | Utah (36) | 27 | USC (10) | 28 | Final | W | 1 |
| 8 | 2017-10-21 | USC (11) | 14 | Notre Dame (10) | 49 | Final | L | -35 |
| 9 | 2017-10-28 | USC (20) | 48 | Arizona State (38) | 17 | Final | W | 31 |
| 10 | 2017-11-04 | Arizona (30) | 35 | USC (17) | 49 | Final | W | 14 |
| 11 | 2017-11-11 | USC (13) | 38 | Colorado (74) | 24 | Final | W | 14 |
| 12 | 2017-11-18 | UCLA (54) | 23 | USC (12) | 28 | Final | W | 5 |
| 13 | 2017-12-01 | Stanford (16) | 28 | USC (15) | 31 | Final | W | 3 |
| 14 | 2017-12-29 | USC (13) | 7 | Ohio State (5) | 24 | Final | L | -17 |