Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-09-12 | The Citadel (178) | 6 | South Florida (96) | 27 | Final | W | 21 |
| 2 | 2020-09-19 | South Florida (96) | 0 | Notre Dame (9) | 52 | Final | L | -52 |
| 3 | 2020-09-26 | South Florida (96) | 0 | Florida Atlantic (26) | 0 | Cancelled | - | - |
| 4 | 2020-10-03 | South Florida (116) | 7 | Cincinnati (11) | 28 | Final | L | -21 |
| 5 | 2020-10-10 | East Carolina (125) | 44 | South Florida (118) | 24 | Final | L | -20 |
| 6 | 2020-10-17 | South Florida (126) | 37 | Temple (111) | 39 | Final | L | -2 |
| 7 | 2020-10-23 | Tulsa (27) | 42 | South Florida (127) | 13 | Final | L | -29 |
| 8 | 2020-11-07 | South Florida (127) | 33 | Memphis (38) | 34 | Final | L | -1 |
| 9 | 2020-11-14 | South Florida (127) | 21 | Houston (53) | 56 | Final | L | -35 |
| 10 | 2020-11-21 | Navy (87) | 0 | South Florida (127) | 0 | Cancelled | - | - |
| 11 | 2020-11-27 | Central Florida (31) | 58 | South Florida (127) | 46 | Final | L | -12 |