Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Ole Miss (65) | 47 | Texas Tech (63) | 27 | Final | W | 20 |
| 2 | 2018-09-08 | Southern Illinois | 41 | Ole Miss | 76 | Final | W | 35 |
| 3 | 2018-09-15 | Alabama (4) | 62 | Ole Miss (65) | 7 | Final | L | -55 |
| 4 | 2018-09-22 | Kent State (136) | 17 | Ole Miss (65) | 38 | Final | W | 21 |
| 5 | 2018-09-29 | Ole Miss (25) | 16 | LSU (4) | 45 | Final | L | -29 |
| 6 | 2018-10-06 | Louisiana-Monroe (110) | 21 | Ole Miss (47) | 70 | Final | W | 49 |
| 7 | 2018-10-13 | Ole Miss (38) | 37 | Arkansas (119) | 33 | Final | W | 4 |
| 8 | 2018-10-20 | Auburn (56) | 31 | Ole Miss (35) | 16 | Final | L | -15 |
| 9 | 2018-11-03 | South Carolina (30) | 48 | Ole Miss (51) | 44 | Final | L | -4 |
| 10 | 2018-11-10 | Ole Miss (52) | 24 | Texas A&M (27) | 38 | Final | L | -14 |
| 11 | 2018-11-17 | Ole Miss (54) | 29 | Vanderbilt (60) | 36 | Final/OT | L | -7 |
| 12 | 2018-11-22 | Mississippi State (14) | 35 | Ole Miss (66) | 3 | Final | L | -32 |