Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2019-09-01 | Houston (79) | 31 | Oklahoma (6) | 49 | Final | W | 18 |
| 2 | 2019-09-07 | South Dakota (179) | 14 | Oklahoma (6) | 70 | Final | W | 56 |
| 3 | 2019-09-14 | Oklahoma (6) | 48 | UCLA (92) | 14 | Final | W | 34 |
| 4 | 2019-09-28 | Texas Tech (76) | 16 | Oklahoma (20) | 55 | Final | W | 39 |
| 5 | 2019-10-05 | Oklahoma (12) | 45 | Kansas (94) | 20 | Final | W | 25 |
| 6 | 2019-10-12 | Oklahoma (11) | 34 | Texas (17) | 27 | Final | W | 7 |
| 7 | 2019-10-19 | West Virginia (72) | 14 | Oklahoma (7) | 52 | Final | W | 38 |
| 8 | 2019-10-26 | Oklahoma (6) | 41 | Kansas State (40) | 48 | Final | L | -7 |
| 9 | 2019-11-09 | Iowa State (35) | 41 | Oklahoma (18) | 42 | Final | W | 1 |
| 10 | 2019-11-16 | Oklahoma (14) | 34 | Baylor (7) | 31 | Final | W | 3 |
| 11 | 2019-11-23 | TCU (47) | 24 | Oklahoma (9) | 28 | Final | W | 4 |
| 12 | 2019-11-30 | Oklahoma (10) | 34 | Oklahoma State (29) | 16 | Final | W | 18 |
| 13 | 2019-12-07 | Baylor (15) | 23 | Oklahoma (7) | 30 | Final(OT) | W | 7 |
| 14 | 2019-12-28 | Oklahoma (5) | 28 | LSU (2) | 63 | Final | L | -35 |