Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-03 | Ohio (102) | 45 | Idaho (126) | 28 | Final | W | 17 |
| 2 | 2015-09-12 | Marshall (29) | 10 | Ohio (102) | 21 | Final | W | 11 |
| 3 | 2015-09-19 | Southeastern Louisiana | 14 | Ohio | 35 | Final | W | 21 |
| 4 | 2015-09-26 | Ohio (28) | 24 | Minnesota (52) | 27 | Final | L | -3 |
| 5 | 2015-10-03 | Ohio (51) | 14 | Akron (76) | 12 | Final | W | 2 |
| 6 | 2015-10-10 | Miami (OH) (120) | 3 | Ohio (45) | 34 | Final | W | 31 |
| 7 | 2015-10-17 | Western Michigan | 49 | Ohio | 14 | Final | L | -35 |
| 8 | 2015-10-24 | Ohio (68) | 17 | Buffalo (101) | 41 | Final | L | -24 |
| 9 | 2015-11-04 | Ohio (87) | 24 | Bowling Green (29) | 62 | Final | L | -38 |
| 10 | 2015-11-10 | Kent State (107) | 0 | Ohio (79) | 27 | Final | W | 27 |
| 11 | 2015-11-17 | Ball State (102) | 31 | Ohio (75) | 48 | Final | W | 17 |
| 12 | 2015-11-24 | Ohio | 26 | Northern Illinois | 21 | Final | W | 5 |
| 13 | 2015-12-19 | Ohio | 29 | Appalachian State | 31 | Final | L | -2 |