Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-08-31 | McNeese State | 35 | Nicholls State | 37 | Final | W | 2 |
| 2 | 2017-09-09 | Nicholls State | 14 | Texas A&M | 24 | Final | L | -10 |
| 3 | 2017-09-16 | Prairie View A&M | 13 | Nicholls State | 44 | Final | W | 31 |
| 4 | 2017-09-23 | Nicholls State | 17 | Sam Houston State | 66 | Final | L | -49 |
| 5 | 2017-09-30 | Nicholls State | 41 | Lamar | 14 | Final | W | 27 |
| 6 | 2017-10-07 | Northwestern State | 10 | Nicholls State | 14 | Final | W | 4 |
| 7 | 2017-10-14 | Abilene Christian | 20 | Nicholls State | 29 | Final | W | 9 |
| 8 | 2017-10-28 | Nicholls State | 38 | Incarnate Word | 31 | Final | W | 7 |
| 9 | 2017-11-04 | Houston Baptist | 17 | Nicholls State | 23 | Final | W | 6 |
| 10 | 2017-11-11 | Nicholls State | 34 | Stephen F. Austin | 13 | Final | W | 21 |
| 11 | 2017-11-16 | Nicholls State | 17 | Southeastern Louisiana | 21 | Final | L | -4 |
| 12 | 2017-11-25 | South Dakota | 38 | Nicholls State | 31 | Final | L | -7 |