Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-16 | Rhode Island | 21 | Harvard | 51 | Final | W | 30 |
| 2 | 2016-09-24 | Harvard | 32 | Brown | 22 | Final | W | 10 |
| 3 | 2016-09-30 | Georgetown | 17 | Harvard | 31 | Final | W | 14 |
| 4 | 2016-10-08 | Cornell | 13 | Harvard | 29 | Final | W | 16 |
| 5 | 2016-10-15 | Harvard | 17 | Holy Cross | 27 | Final | L | -10 |
| 6 | 2016-10-22 | Harvard | 23 | Princeton | 20 | Final/OT | W | 3 |
| 7 | 2016-10-29 | Harvard (158) | 23 | Dartmouth (193) | 21 | Final | W | 2 |
| 8 | 2016-11-05 | Columbia (224) | 21 | Harvard (159) | 28 | Final | W | 7 |
| 9 | 2016-11-11 | Harvard (156) | 14 | Penn (179) | 27 | Final | L | -13 |
| 10 | 2016-11-19 | Yale (231) | 21 | Harvard (165) | 14 | Final | L | -7 |