Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-05 | Old Dominion (93) | 38 | Eastern Michigan (125) | 34 | Final | L | -4 |
| 2 | 2015-09-12 | Eastern Michigan (125) | 48 | Wyoming (87) | 29 | Final | W | 19 |
| 3 | 2015-09-19 | Ball State | 28 | Eastern Michigan | 17 | Final | L | -11 |
| 4 | 2015-09-26 | Army | 58 | Eastern Michigan | 36 | Final | L | -22 |
| 5 | 2015-10-03 | Eastern Michigan | 22 | LSU | 44 | Final | L | -22 |
| 6 | 2015-10-10 | Akron | 47 | Eastern Michigan | 21 | Final | L | -26 |
| 7 | 2015-10-17 | Eastern Michigan | 20 | Toledo | 63 | Final | L | -43 |
| 8 | 2015-10-24 | Eastern Michigan | 21 | Northern Illinois | 49 | Final | L | -28 |
| 9 | 2015-10-29 | Western Michigan | 58 | Eastern Michigan | 28 | Final | L | -30 |
| 10 | 2015-11-07 | Eastern Michigan | 13 | Miami (OH) | 28 | Final | L | -15 |
| 11 | 2015-11-14 | Massachusetts | 28 | Eastern Michigan | 17 | Final | L | -11 |
| 12 | 2015-11-27 | Eastern Michigan | 28 | Central Michigan | 35 | Final | L | -7 |