Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-08-30 | Wake Forest (34) | 23 | Tulane (82) | 17 | Final/OT | W | 6 |
| 2 | 2018-09-08 | Towson (184) | 20 | Wake Forest (34) | 51 | Final | W | 31 |
| 3 | 2018-09-13 | Boston College (31) | 41 | Wake Forest (34) | 34 | Final | L | -7 |
| 4 | 2018-09-22 | Notre Dame (10) | 56 | Wake Forest (34) | 27 | Final | L | -29 |
| 5 | 2018-09-29 | Rice (120) | 24 | Wake Forest (82) | 56 | Final | W | 32 |
| 6 | 2018-10-06 | Clemson (6) | 63 | Wake Forest (64) | 3 | Final | L | -60 |
| 7 | 2018-10-20 | Wake Forest (73) | 17 | Florida State (80) | 38 | Final | L | -21 |
| 8 | 2018-10-27 | Wake Forest (91) | 56 | Louisville (111) | 35 | Final | W | 21 |
| 9 | 2018-11-03 | Syracuse (23) | 41 | Wake Forest (84) | 24 | Final | L | -17 |
| 10 | 2018-11-08 | Wake Forest (88) | 27 | North Carolina State (25) | 23 | Final | W | 4 |
| 11 | 2018-11-17 | Pittsburgh (39) | 34 | Wake Forest (74) | 13 | Final | L | -21 |
| 12 | 2018-11-24 | Wake Forest (83) | 59 | Duke (34) | 7 | Final | W | 52 |
| 13 | 2018-12-22 | Memphis (61) | 34 | Wake Forest (60) | 37 | Final | W | 3 |