Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-03 | Virginia Tech (20) | 24 | Florida State (39) | 3 | Final | W | 21 |
| 2 | 2018-09-08 | William & Mary (205) | 17 | Virginia Tech (20) | 62 | Final | W | 45 |
| 3 | 2018-09-15 | East Carolina (128) | 0 | Virginia Tech (20) | 0 | Canceled | – | – |
| 4 | 2018-09-22 | Virginia Tech (20) | 35 | Old Dominion (112) | 49 | Final | L | -14 |
| 5 | 2018-09-29 | Virginia Tech (76) | 31 | Duke (7) | 14 | Final | W | 17 |
| 6 | 2018-10-06 | Notre Dame (3) | 45 | Virginia Tech (42) | 23 | Final | L | -22 |
| 7 | 2018-10-13 | Virginia Tech (57) | 22 | North Carolina (101) | 19 | Final | W | 3 |
| 8 | 2018-10-25 | Georgia Tech (78) | 49 | Virginia Tech (55) | 28 | Final | L | -21 |
| 9 | 2018-11-03 | Boston College (34) | 31 | Virginia Tech (72) | 21 | Final | L | -10 |
| 10 | 2018-11-10 | Virginia Tech (77) | 22 | Pittsburgh (46) | 52 | Final | L | -30 |
| 11 | 2018-11-17 | Miami (52) | 38 | Virginia Tech (88) | 14 | Final | L | -24 |
| 12 | 2018-11-23 | Virginia (49) | 31 | Virginia Tech (91) | 34 | Final/OT | W | 3 |
| 13 | 2018-12-01 | Marshall (54) | 20 | Virginia Tech (85) | 41 | Final | W | 21 |
| 14 | 2018-12-31 | Cincinnati (21) | 35 | Virginia Tech (72) | 31 | Final | L | -4 |