Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-08-30 | Wake Forest (34) | 23 | Tulane (82) | 17 | Final/OT | L | -6 |
| 2 | 2018-09-08 | Nicholls State | 17 | Tulane | 42 | Final | W | 25 |
| 3 | 2018-09-15 | Tulane (82) | 24 | UAB (89) | 31 | Final | L | -7 |
| 4 | 2018-09-22 | Tulane (82) | 6 | Ohio State (5) | 49 | Final | L | -43 |
| 5 | 2018-09-28 | Memphis (63) | 24 | Tulane (116) | 40 | Final | W | 16 |
| 6 | 2018-10-06 | Tulane (81) | 21 | Cincinnati (16) | 37 | Final | L | -16 |
| 7 | 2018-10-20 | SMU (95) | 27 | Tulane (87) | 23 | Final | L | -4 |
| 8 | 2018-10-27 | Tulane (103) | 24 | Tulsa (124) | 17 | Final | W | 7 |
| 9 | 2018-11-03 | Tulane (100) | 41 | South Florida (49) | 15 | Final | W | 26 |
| 10 | 2018-11-10 | East Carolina (121) | 18 | Tulane (85) | 24 | Final | W | 6 |
| 11 | 2018-11-15 | Tulane (82) | 17 | Houston (56) | 48 | Final | L | -31 |
| 12 | 2018-11-24 | Navy (108) | 28 | Tulane (94) | 29 | Final | W | 1 |
| 13 | 2018-12-15 | Tulane (89) | 41 | Louisiana (83) | 24 | Final | W | 17 |