Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Syracuse (27) | 26 | Tennessee (9) | 45 | Final | L | -19 |
| 2 | 2025-09-06 | Connecticut (61) | 20 | Syracuse (27) | 27 | Final/OT | W | 7 |
| 3 | 2025-09-12 | Colgate (246) | 24 | Syracuse (27) | 66 | Final | W | 42 |
| 4 | 2025-09-20 | Syracuse (48) | 34 | Clemson (81) | 21 | Final | W | 13 |
| 5 | 2025-09-27 | Duke (46) | 38 | Syracuse (68) | 3 | Final | L | -35 |
| 6 | 2025-10-04 | Syracuse (80) | 18 | SMU (65) | 31 | Final | L | -13 |
| 7 | 2025-10-18 | Pittsburgh (41) | 30 | Syracuse (80) | 13 | Final | L | -17 |
| 8 | 2025-10-25 | Syracuse (80) | Georgia Tech (7) | Scheduled – 12:00 PM | – | – | ||
| 9 | 2025-10-31 | North Carolina (79) | 0 | Syracuse (27) | 0 | Scheduled – 7:30 PM | – | – |
| 10 | 2025-11-08 | Syracuse (27) | 0 | Miami (15) | 0 | Scheduled – TBD | – | – |
| 11 | 2025-11-22 | Syracuse (27) | 0 | Notre Dame (3) | 0 | Scheduled – 3:30 PM | – | – |
| 12 | 2025-11-29 | Boston College (51) | 0 | Syracuse (27) | 0 | Scheduled – TBD | – | – |