Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-08-31 | Syracuse | 55 | Western Michigan | 42 | Final | W | 13 |
| 2 | 2018-09-08 | Wagner (219) | 10 | Syracuse (77) | 62 | Final | W | 52 |
| 3 | 2018-09-15 | Florida State (39) | 7 | Syracuse (77) | 30 | Final | W | 23 |
| 4 | 2018-09-22 | Connecticut | 21 | Syracuse | 51 | Final | W | 30 |
| 5 | 2018-09-29 | Syracuse (13) | 23 | Clemson (11) | 27 | Final | L | -4 |
| 6 | 2018-10-06 | Syracuse (19) | 37 | Pittsburgh (97) | 44 | Final/OT | L | -7 |
| 7 | 2018-10-20 | North Carolina (113) | 37 | Syracuse (45) | 40 | Final/2OT | W | 3 |
| 8 | 2018-10-27 | North Carolina State (15) | 41 | Syracuse (40) | 51 | Final | W | 10 |
| 9 | 2018-11-03 | Syracuse (23) | 41 | Wake Forest (84) | 24 | Final | W | 17 |
| 10 | 2018-11-09 | Louisville (116) | 23 | Syracuse (21) | 54 | Final | W | 31 |
| 11 | 2018-11-17 | Syracuse (18) | 3 | Notre Dame (3) | 36 | Final | L | -33 |
| 12 | 2018-11-24 | Syracuse (23) | 42 | Boston College (42) | 21 | Final | W | 21 |
| 13 | 2018-12-28 | West Virginia (22) | 18 | Syracuse (18) | 34 | Final | W | 16 |