Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | South Carolina State | 6 | Georgia Southern | 37 | Final | L | -31 |
| 2 | 2018-09-08 | South Carolina State | 0 | Central Florida | 38 | Final | L | -38 |
| 3 | 2018-09-15 | North Carolina Central | 0 | South Carolina State | 0 | Postponed | – | – |
| 4 | 2018-09-22 | Norfolk State | 17 | South Carolina State | 7 | Final | L | -10 |
| 5 | 2018-09-27 | South Carolina State (228) | 16 | North Carolina A&T (139) | 31 | Final | L | -15 |
| 6 | 2018-10-06 | South Carolina State (228) | 21 | Morgan State (184) | 18 | Final | W | 3 |
| 7 | 2018-10-13 | Bethune-Cookman (202) | 28 | South Carolina State (209) | 26 | Final | L | -2 |
| 8 | 2018-10-20 | Delaware State (254) | 19 | South Carolina State (222) | 30 | Final | W | 11 |
| 9 | 2018-10-27 | South Carolina State (221) | 27 | Howard (177) | 21 | Final | W | 6 |
| 10 | 2018-11-10 | South Carolina State (203) | 44 | Florida A&M (167) | 21 | Final | W | 23 |
| 11 | 2018-11-17 | Savannah State (230) | 17 | South Carolina State (192) | 21 | Final | W | 4 |
| 12 | 2018-11-24 | North Carolina Central (225) | 21 | South Carolina State (189) | 17 | Final | L | -4 |