Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | SMU (48) | 23 | North Texas (54) | 46 | Final | L | -23 |
| 2 | 2018-09-07 | TCU (15) | 42 | SMU (48) | 12 | Final | L | -30 |
| 3 | 2018-09-15 | SMU (48) | 20 | Michigan (27) | 45 | Final | L | -25 |
| 4 | 2018-09-22 | Navy (44) | 30 | SMU (48) | 31 | Final/OT | W | 1 |
| 5 | 2018-09-29 | Houston Baptist (231) | 27 | SMU (93) | 63 | Final | W | 36 |
| 6 | 2018-10-06 | SMU (86) | 20 | Central Florida (18) | 48 | Final | L | -28 |
| 7 | 2018-10-20 | SMU (95) | 27 | Tulane (87) | 23 | Final | W | 4 |
| 8 | 2018-10-27 | Cincinnati (34) | 26 | SMU (90) | 20 | Final/OT | L | -6 |
| 9 | 2018-11-03 | Houston (27) | 31 | SMU (94) | 45 | Final | W | 14 |
| 10 | 2018-11-10 | SMU (74) | 62 | Connecticut (149) | 50 | Final | W | 12 |
| 11 | 2018-11-16 | Memphis (85) | 28 | SMU (80) | 18 | Final | L | -10 |
| 12 | 2018-11-24 | SMU (89) | 24 | Tulsa (134) | 27 | Final | L | -3 |