Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-08-25 | Prairie View A&M | 28 | Rice | 31 | Final | W | 3 |
| 2 | 2018-09-01 | Houston (46) | 45 | Rice (153) | 27 | Final | L | -18 |
| 3 | 2018-09-08 | Rice | 29 | Hawaii | 43 | Final | L | -14 |
| 4 | 2018-09-22 | Rice (153) | 22 | Southern Miss (72) | 40 | Final | L | -18 |
| 5 | 2018-09-29 | Rice (120) | 24 | Wake Forest (82) | 56 | Final | L | -32 |
| 6 | 2018-10-06 | UTSA (118) | 20 | Rice (127) | 3 | Final | L | -17 |
| 7 | 2018-10-13 | UAB (41) | 42 | Rice (145) | 0 | Final | L | -42 |
| 8 | 2018-10-20 | Rice (146) | 17 | Florida International (61) | 36 | Final | L | -19 |
| 9 | 2018-10-27 | Rice (146) | 17 | North Texas (45) | 41 | Final | L | -24 |
| 10 | 2018-11-03 | UTEP (189) | 34 | Rice (152) | 26 | Final | L | -8 |
| 11 | 2018-11-10 | Rice (164) | 13 | Louisiana Tech (56) | 28 | Final | L | -15 |
| 12 | 2018-11-17 | Rice (169) | 10 | LSU (8) | 42 | Final | L | -32 |
| 13 | 2018-11-24 | Old Dominion (112) | 13 | Rice (169) | 27 | Final | W | 14 |