Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Florida Atlantic | 14 | Oklahoma | 63 | Final | W | 49 |
| 2 | 2018-09-08 | UCLA (55) | 21 | Oklahoma (7) | 49 | Final | W | 28 |
| 3 | 2018-09-15 | Oklahoma (7) | 37 | Iowa State (38) | 27 | Final | W | 10 |
| 4 | 2018-09-22 | Army (40) | 21 | Oklahoma (7) | 28 | Final/OT | W | 7 |
| 5 | 2018-09-29 | Baylor (47) | 33 | Oklahoma (5) | 66 | Final | W | 33 |
| 6 | 2018-10-06 | Texas (21) | 48 | Oklahoma (7) | 45 | Final | L | -3 |
| 7 | 2018-10-20 | Oklahoma (8) | 52 | TCU (50) | 27 | Final | W | 25 |
| 8 | 2018-10-27 | Kansas State (79) | 14 | Oklahoma (6) | 51 | Final | W | 37 |
| 9 | 2018-11-03 | Oklahoma (7) | 51 | Texas Tech (35) | 46 | Final | W | 5 |
| 10 | 2018-11-10 | Oklahoma State (61) | 47 | Oklahoma (6) | 48 | Final | W | 1 |
| 11 | 2018-11-17 | Kansas (110) | 40 | Oklahoma (6) | 55 | Final | W | 15 |
| 12 | 2018-11-23 | Oklahoma (7) | 59 | West Virginia (16) | 56 | Final | W | 3 |
| 13 | 2018-12-01 | Texas (25) | 27 | Oklahoma (8) | 39 | Final | W | 12 |
| 14 | 2018-12-29 | Oklahoma (8) | 34 | Alabama (1) | 45 | Final | L | -11 |