Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-08-25 | Duquesne | 15 | Massachusetts | 63 | Final | W | 48 |
| 2 | 2018-09-01 | Massachusetts | 21 | Boston College | 55 | Final | L | -34 |
| 3 | 2018-09-08 | Massachusetts | 13 | Georgia Southern | 34 | Final | L | -21 |
| 4 | 2018-09-15 | Massachusetts | 24 | Florida International | 63 | Final | L | -39 |
| 5 | 2018-09-22 | Charlotte | 31 | Massachusetts | 49 | Final | W | 18 |
| 6 | 2018-09-29 | Massachusetts (100) | 42 | Ohio (98) | 58 | Final | L | -16 |
| 7 | 2018-10-06 | South Florida (25) | 58 | Massachusetts (106) | 42 | Final | L | -16 |
| 8 | 2018-10-20 | Coastal Carolina (86) | 24 | Massachusetts (106) | 13 | Final | L | -11 |
| 9 | 2018-10-27 | Massachusetts (113) | 22 | Connecticut (130) | 17 | Final | W | 5 |
| 10 | 2018-11-03 | Liberty (90) | 59 | Massachusetts (108) | 62 | Final/3OT | W | 3 |
| 11 | 2018-11-10 | BYU (73) | 35 | Massachusetts (106) | 16 | Final | L | -19 |
| 12 | 2018-11-17 | Massachusetts (106) | 27 | Georgia (4) | 66 | Final | L | -39 |