Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Louisiana Tech | 30 | South Alabama | 26 | Final | W | 4 |
| 2 | 2018-09-08 | Southern | 17 | Louisiana Tech | 54 | Final | W | 37 |
| 3 | 2018-09-22 | Louisiana Tech | 21 | LSU | 38 | Final | L | -17 |
| 4 | 2018-09-29 | Louisiana Tech (61) | 29 | North Texas (12) | 27 | Final | W | 2 |
| 5 | 2018-10-06 | UAB (62) | 28 | Louisiana Tech (33) | 7 | Final | L | -21 |
| 6 | 2018-10-13 | Louisiana Tech (65) | 31 | UTSA (109) | 3 | Final | W | 28 |
| 7 | 2018-10-20 | UTEP (179) | 24 | Louisiana Tech (54) | 31 | Final | W | 7 |
| 8 | 2018-10-26 | Louisiana Tech (57) | 21 | Florida Atlantic (93) | 13 | Final | W | 8 |
| 9 | 2018-11-03 | Louisiana Tech (50) | 3 | Mississippi State (17) | 45 | Final | L | -42 |
| 10 | 2018-11-10 | Rice (164) | 13 | Louisiana Tech (56) | 28 | Final | W | 15 |
| 11 | 2018-11-17 | Louisiana Tech (59) | 20 | Southern Miss (99) | 21 | Final | L | -1 |
| 12 | 2018-11-24 | Western Kentucky (143) | 30 | Louisiana Tech (78) | 15 | Final | L | -15 |
| 13 | 2018-12-22 | Hawaii (88) | 14 | Louisiana Tech (94) | 31 | Final | W | 17 |