Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Nicholls State | 26 | Kansas | 23 | Final/OT | L | -3 |
| 2 | 2018-09-08 | Kansas | 31 | Central Michigan | 7 | Final | W | 24 |
| 3 | 2018-09-15 | Rutgers (99) | 14 | Kansas (160) | 55 | Final | W | 41 |
| 4 | 2018-09-22 | Kansas (160) | 7 | Baylor (139) | 26 | Final | L | -19 |
| 5 | 2018-09-29 | Oklahoma State (32) | 48 | Kansas (95) | 28 | Final | L | -20 |
| 6 | 2018-10-06 | Kansas (102) | 22 | West Virginia (10) | 38 | Final | L | -16 |
| 7 | 2018-10-20 | Kansas (112) | 16 | Texas Tech (28) | 48 | Final | L | -32 |
| 8 | 2018-10-27 | TCU (58) | 26 | Kansas (117) | 27 | Final | W | 1 |
| 9 | 2018-11-03 | Iowa State (32) | 27 | Kansas (105) | 3 | Final | L | -24 |
| 10 | 2018-11-10 | Kansas (107) | 17 | Kansas State (94) | 21 | Final | L | -4 |
| 11 | 2018-11-17 | Kansas (110) | 40 | Oklahoma (6) | 55 | Final | L | -15 |
| 12 | 2018-11-23 | Texas (22) | 24 | Kansas (109) | 17 | Final | L | -7 |