Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Shaw | 10 | Hampton | 38 | Final | W | 28 |
| 2 | 2018-09-08 | Hampton (196) | 28 | Monmouth (161) | 56 | Final | L | -28 |
| 3 | 2018-09-15 | Tennessee State | 0 | Hampton | 0 | Canceled | – | – |
| 4 | 2018-09-22 | Hampton (196) | 0 | Northern Iowa (132) | 44 | Final | L | -44 |
| 5 | 2018-09-29 | Charleston Southern (217) | 48 | Hampton (242) | 14 | Final | L | -34 |
| 6 | 2018-10-06 | Lane | 8 | Hampton | 41 | Final | W | 33 |
| 7 | 2018-10-13 | Hampton (244) | 24 | Presbyterian (234) | 23 | Final | W | 1 |
| 8 | 2018-10-27 | VU of Lynchburg | 28 | Hampton | 51 | Final | W | 23 |
| 9 | 2018-11-03 | Hampton | 51 | SUNY Maritime | 10 | Final | W | 41 |
| 10 | 2018-11-10 | Hampton (228) | 54 | Mississippi Valley State (252) | 39 | Final | W | 15 |
| 11 | 2018-11-17 | St. Andrews | 17 | Hampton | 44 | Final | W | 27 |