Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Langston | 7 | Grambling (231) | 55 | Final | W | 48 |
| 2 | 2025-09-06 | Grambling (231) | 0 | Ohio State (1) | 0 | Scheduled – 3:30 PM | – | – |
| 3 | 2025-09-13 | Kentucky State | 0 | Grambling (231) | 0 | Scheduled – 6:00 PM | – | – |
| 4 | 2025-09-20 | East Texas A&M (235) | 0 | Grambling (231) | 0 | Scheduled – 6:00 PM | – | – |
| 5 | 2025-09-27 | Grambling (231) | 0 | Prairie View A&M (236) | 0 | Scheduled – 6:00 PM | – | – |
| 6 | 2025-10-11 | Texas Southern (230) | 0 | Grambling (231) | 0 | Scheduled – 6:00 PM | – | – |
| 7 | 2025-10-18 | Grambling (231) | 0 | Arkansas-Pine Bluff (252) | 0 | Scheduled – 2:00 PM | – | – |
| 8 | 2025-10-25 | Jackson State (136) | 0 | Grambling (231) | 0 | Scheduled – 3:00 PM | – | – |
| 9 | 2025-10-31 | Alabama A&M (225) | 0 | Grambling (231) | 0 | Scheduled – TBD | – | – |
| 10 | 2025-11-07 | Bethune-Cookman (253) | 0 | Grambling (231) | 0 | Scheduled – TBD | – | – |
| 11 | 2025-11-15 | Grambling (231) | 0 | Alcorn State (215) | 0 | Scheduled – 2:00 PM | – | – |
| 12 | 2025-11-29 | Grambling (231) | 0 | Southern (199) | 0 | Scheduled – 1:00 PM | – | – |