Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Mars Hill | 7 | East Tennessee State | 28 | Final | W | 21 |
| 2 | 2018-09-08 | East Tennessee State | 3 | Tennessee | 59 | Final | L | -56 |
| 3 | 2018-09-14 | East Tennessee State | 27 | Virginia Military | 24 | Final | W | 3 |
| 4 | 2018-09-22 | Furman | 27 | East Tennessee State | 29 | Final | W | 2 |
| 5 | 2018-09-29 | Chattanooga (135) | 14 | East Tennessee State (180) | 17 | Final | W | 3 |
| 6 | 2018-10-06 | Gardner-Webb (241) | 0 | East Tennessee State (158) | 45 | Final | W | 45 |
| 7 | 2018-10-13 | East Tennessee State (152) | 26 | The Citadel (189) | 23 | Final | W | 3 |
| 8 | 2018-10-20 | East Tennessee State (149) | 17 | Wofford (162) | 30 | Final | L | -13 |
| 9 | 2018-10-27 | Western Carolina (236) | 43 | East Tennessee State (162) | 45 | Final/3OT | W | 2 |
| 10 | 2018-11-03 | East Tennessee State (159) | 21 | Mercer (198) | 18 | Final | W | 3 |
| 11 | 2018-11-17 | Samford (175) | 38 | East Tennessee State (150) | 27 | Final | L | -11 |
| 12 | 2018-11-24 | East Tennessee State (166) | 27 | Jacksonville State (141) | 34 | Final | L | -7 |