Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Central Michigan | 20 | Kentucky | 35 | Final | L | -15 |
| 2 | 2018-09-08 | Kansas | 31 | Central Michigan | 7 | Final | L | -24 |
| 3 | 2018-09-15 | Central Michigan | 16 | Northern Illinois | 24 | Final | L | -8 |
| 4 | 2018-09-22 | Maine | 5 | Central Michigan | 17 | Final | W | 12 |
| 5 | 2018-09-29 | Central Michigan (127) | 20 | Michigan State (31) | 31 | Final | L | -11 |
| 6 | 2018-10-06 | Buffalo (51) | 34 | Central Michigan (123) | 24 | Final | L | -10 |
| 7 | 2018-10-13 | Ball State (110) | 24 | Central Michigan (127) | 23 | Final | L | -1 |
| 8 | 2018-10-20 | Western Michigan (57) | 35 | Central Michigan (132) | 10 | Final | L | -25 |
| 9 | 2018-10-27 | Central Michigan (132) | 10 | Akron (88) | 17 | Final | L | -7 |
| 10 | 2018-11-03 | Central Michigan (132) | 7 | Eastern Michigan (79) | 17 | Final | L | -10 |
| 11 | 2018-11-10 | Bowling Green (152) | 24 | Central Michigan (139) | 13 | Final | L | -11 |
| 12 | 2018-11-23 | Central Michigan (147) | 13 | Toledo (72) | 51 | Final | L | -38 |