Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Appalachian State | 38 | Penn State | 45 | Final/OT | L | -7 |
| 2 | 2018-09-08 | Appalachian State | 45 | Charlotte | 9 | Final | W | 36 |
| 3 | 2018-09-15 | Southern Miss | 0 | Appalachian State | 0 | Postponed | – | – |
| 4 | 2018-09-22 | Gardner-Webb | 7 | Appalachian State | 72 | Final | W | 65 |
| 5 | 2018-09-29 | South Alabama (110) | 7 | Appalachian State (37) | 52 | Final | W | 45 |
| 6 | 2018-10-09 | Appalachian State (30) | 35 | Arkansas State (71) | 9 | Final | W | 26 |
| 7 | 2018-10-20 | Louisiana (90) | 17 | Appalachian State (20) | 27 | Final | W | 10 |
| 8 | 2018-10-25 | Appalachian State (19) | 14 | Georgia Southern (38) | 34 | Final | L | -20 |
| 9 | 2018-11-03 | Appalachian State (33) | 23 | Coastal Carolina (74) | 7 | Final | W | 16 |
| 10 | 2018-11-10 | Appalachian State (32) | 38 | Texas State (128) | 7 | Final | W | 31 |
| 11 | 2018-11-17 | Georgia State (129) | 17 | Appalachian State (31) | 45 | Final | W | 28 |
| 12 | 2018-11-24 | Troy (41) | 10 | Appalachian State (27) | 21 | Final | W | 11 |
| 13 | 2018-12-01 | Louisiana (79) | 19 | Appalachian State (22) | 30 | Final | W | 11 |
| 14 | 2018-12-15 | Middle Tennessee (57) | 13 | Appalachian State (20) | 45 | Final | W | 32 |