Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Charleston Southern (250) | 3 | Vanderbilt (40) | 45 | Final | W | 42 |
| 2 | 2025-09-06 | Vanderbilt (40) | 0 | Virginia Tech (45) | 0 | Scheduled – 7:30 PM | – | – |
| 3 | 2025-09-13 | Vanderbilt (40) | 0 | South Carolina (13) | 0 | Scheduled – TBD | – | – |
| 4 | 2025-09-20 | Georgia State (116) | 0 | Vanderbilt (40) | 0 | Scheduled – 6:30 PM | – | – |
| 5 | 2025-09-27 | Utah State (120) | 0 | Vanderbilt (40) | 0 | Scheduled – 11:45 AM | – | – |
| 6 | 2025-10-03 | Vanderbilt (40) | 0 | Alabama (10) | 0 | Scheduled – TBD | – | – |
| 7 | 2025-10-17 | LSU (19) | 0 | Vanderbilt (40) | 0 | Scheduled – TBD | – | – |
| 8 | 2025-10-24 | Missouri (23) | 0 | Vanderbilt (40) | 0 | Scheduled – TBD | – | – |
| 9 | 2025-11-01 | Vanderbilt (40) | 0 | Texas (4) | 0 | Scheduled – 11:00 AM | – | – |
| 10 | 2025-11-07 | Auburn (57) | 0 | Vanderbilt (40) | 0 | Scheduled – TBD | – | – |
| 11 | 2025-11-21 | Kentucky (63) | 0 | Vanderbilt (40) | 0 | Scheduled – TBD | – | – |
| 12 | 2025-11-29 | Vanderbilt (40) | 0 | Tennessee (9) | 0 | Scheduled – TBD | – | – |