Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Prairie View A&M (236) | 22 | Texas Southern (230) | 21 | Final | L | -1 |
| 2 | 2025-09-06 | Texas Southern (230) | 3 | California (82) | 35 | Final | L | -32 |
| 3 | 2025-09-13 | Lamar (181) | 31 | Texas Southern (230) | 7 | Final | L | -24 |
| 4 | 2025-09-27 | Texas Southern (226) | 23 | Mississippi Valley State (262) | 20 | Final | W | 3 |
| 5 | 2025-10-04 | Arkansas-Pine Bluff (261) | 7 | Texas Southern (206) | 51 | Final | W | 44 |
| 6 | 2025-10-11 | Texas Southern (206) | Grambling (212) | Scheduled – 6:00 PM | – | – | ||
| 7 | 2025-10-18 | Virginia Lynchburg | 0 | Texas Southern (230) | 0 | Scheduled – 2:00 PM | – | – |
| 8 | 2025-11-01 | Alcorn State (215) | 0 | Texas Southern (230) | 0 | Scheduled – 2:00 PM | – | – |
| 9 | 2025-11-08 | Texas Southern (230) | 0 | Alabama State (208) | 0 | Scheduled – 2:00 PM | – | – |
| 10 | 2025-11-14 | Texas Southern (230) | 0 | Southern (199) | 0 | Scheduled – TBD | – | – |
| 11 | 2025-11-22 | Alabama A&M (225) | 0 | Texas Southern (230) | 0 | Scheduled – 2:00 PM | – | – |