Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | South Dakota (105) | 7 | Iowa State (21) | 55 | Final | L | -48 |
| 2 | 2025-09-06 | South Dakota (105) | 13 | Lamar (181) | 20 | Final | L | -7 |
| 3 | 2025-09-13 | Northern Colorado (249) | 17 | South Dakota (105) | 24 | Final/OT | W | 7 |
| 4 | 2025-09-20 | Drake (230) | 21 | South Dakota (185) | 42 | Final | W | 21 |
| 5 | 2025-09-27 | South Dakota (193) | 13 | North Dakota State (132) | 51 | Final | L | -38 |
| 6 | 2025-10-04 | Murray State (244) | 24 | South Dakota (180) | 49 | Final | W | 25 |
| 7 | 2025-10-11 | South Dakota (167) | 19 | Indiana State (228) | 14 | Final | W | 5 |
| 8 | 2025-10-18 | South Dakota (162) | 17 | Northern Iowa (208) | 14 | Final | W | 3 |
| 9 | 2025-10-25 | Illinois State (165) | 21 | South Dakota (171) | 13 | Final | L | -8 |
| 10 | 2025-11-01 | North Dakota (141) | 21 | South Dakota (161) | 26 | Final | W | 5 |
| 11 | 2025-11-08 | South Dakota State (142) | 17 | South Dakota (157) | 24 | Final | W | 7 |
| 12 | 2025-11-15 | South Dakota (153) | 53 | Southern Illinois (170) | 51 | Final/5OT | W | 2 |
| 13 | 2025-11-29 | Drake (177) | South Dakota (155) | Scheduled – 12:00 PM | – | – |