Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-28 | McKendree | 24 | Indiana State (222) | 41 | Final | W | 17 |
| 2 | 2025-09-06 | Eastern Illinois (226) | 14 | Indiana State (222) | 38 | Final | W | 24 |
| 3 | 2025-09-12 | Indiana State (222) | 0 | Indiana (6) | 73 | Final | L | -73 |
| 4 | 2025-09-20 | Indiana State (204) | 20 | Montana (146) | 63 | Final | L | -43 |
| 5 | 2025-10-04 | Indiana State (210) | 27 | Southern Illinois (146) | 55 | Final | L | -28 |
| 6 | 2025-10-11 | South Dakota (180) | Indiana State (210) | Scheduled – 1:00 PM | – | – | ||
| 7 | 2025-10-18 | North Dakota State (69) | 0 | Indiana State (222) | 0 | Scheduled – 1:00 PM | – | – |
| 8 | 2025-10-25 | Indiana State (222) | 0 | North Dakota (174) | 0 | Scheduled – 3:00 PM | – | – |
| 9 | 2025-11-01 | Indiana State (222) | 0 | South Dakota State (92) | 0 | Scheduled – 2:00 PM | – | – |
| 10 | 2025-11-08 | Illinois State (139) | 0 | Indiana State (222) | 0 | Scheduled – 1:00 PM | – | – |
| 11 | 2025-11-15 | Indiana State (222) | 0 | Youngstown State (191) | 0 | Scheduled – 12:00 PM | – | – |
| 12 | 2025-11-22 | Murray State (251) | 0 | Indiana State (222) | 0 | Scheduled – 1:00 PM | – | – |