Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Illinois State (139) | 3 | Oklahoma (41) | 35 | Final | L | -32 |
| 2 | 2025-09-06 | Morehead State (220) | 13 | Illinois State (139) | 41 | Final | W | 28 |
| 3 | 2025-09-13 | Illinois State (139) | 42 | Eastern Illinois (226) | 30 | Final | W | 12 |
| 4 | 2025-09-20 | North Alabama (247) | 36 | Illinois State (157) | 38 | Final/2OT | W | 2 |
| 5 | 2025-10-04 | North Dakota State (127) | 33 | Illinois State (171) | 16 | Final | L | -17 |
| 6 | 2025-10-11 | Illinois State (169) | 46 | Murray State (241) | 32 | Final | W | 14 |
| 7 | 2025-10-18 | Youngstown State (159) | 40 | Illinois State (175) | 35 | Final | L | -5 |
| 8 | 2025-10-25 | Illinois State (165) | 21 | South Dakota (171) | 13 | Final | W | 8 |
| 9 | 2025-11-01 | Northern Iowa (224) | 16 | Illinois State (162) | 31 | Final | W | 15 |
| 10 | 2025-11-08 | Illinois State (154) | 52 | Indiana State (212) | 20 | Final | W | 32 |
| 11 | 2025-11-15 | Illinois State (149) | 35 | South Dakota State (154) | 21 | Final | W | 14 |
| 12 | 2025-11-22 | Southern Illinois (160) | 37 | Illinois State (159) | 7 | Final | L | -30 |
| 13 | 2025-11-29 | Illinois State (159) | Southeastern Louisiana (147) | Scheduled – 12:00 PM | – | – |