Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Illinois State (139) | 3 | Oklahoma (41) | 35 | Final | L | -32 |
| 2 | 2025-09-06 | Morehead State (220) | 13 | Illinois State (139) | 41 | Final | W | 28 |
| 3 | 2025-09-13 | Illinois State (139) | 42 | Eastern Illinois (226) | 30 | Final | W | 12 |
| 4 | 2025-09-20 | North Alabama (247) | 36 | Illinois State (157) | 38 | Final/2OT | W | 2 |
| 5 | 2025-10-04 | North Dakota State (127) | 33 | Illinois State (171) | 16 | Final | L | -17 |
| 6 | 2025-10-11 | Illinois State (171) | Murray State (244) | Scheduled – 6:00 PM | – | – | ||
| 7 | 2025-10-18 | Youngstown State (191) | 0 | Illinois State (139) | 0 | Scheduled – 2:00 PM | – | – |
| 8 | 2025-10-25 | Illinois State (139) | 0 | South Dakota (105) | 0 | Scheduled – 1:00 PM | – | – |
| 9 | 2025-11-01 | Northern Iowa (206) | 0 | Illinois State (139) | 0 | Scheduled – 2:00 PM | – | – |
| 10 | 2025-11-08 | Illinois State (139) | 0 | Indiana State (222) | 0 | Scheduled – 1:00 PM | – | – |
| 11 | 2025-11-15 | Illinois State (139) | 0 | South Dakota State (92) | 0 | Scheduled – 2:00 PM | – | – |
| 12 | 2025-11-22 | Southern Illinois (184) | 0 | Illinois State (139) | 0 | Scheduled – 12:00 PM | – | – |