Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-28 | Alabama State (208) | 42 | UAB (119) | 52 | Final | L | -10 |
| 2 | 2025-09-06 | Alabama State (208) | 30 | Southern (199) | 7 | Final | W | 23 |
| 3 | 2025-09-13 | Miles | 9 | Alabama State (208) | 37 | Final | W | 28 |
| 4 | 2025-09-27 | Alabama State (165) | 42 | Florida A&M (255) | 14 | Final | W | 28 |
| 5 | 2025-10-04 | Bethune-Cookman (224) | 35 | Alabama State (155) | 52 | Final | W | 17 |
| 6 | 2025-10-11 | Alabama State (170) | 34 | Jackson State (152) | 38 | Final | L | -4 |
| 7 | 2025-10-25 | Alabama State (163) | 56 | Alabama A&M (228) | 13 | Final | W | 43 |
| 8 | 2025-11-01 | Alabama State (157) | 31 | Prairie View A&M (182) | 28 | Final | W | 3 |
| 9 | 2025-11-08 | Texas Southern (220) | 24 | Alabama State (155) | 42 | Final | W | 18 |
| 10 | 2025-11-15 | Alabama State (158) | 41 | Mississippi Valley State (265) | 3 | Final | W | 38 |
| 11 | 2025-11-22 | Arkansas-Pine Bluff (256) | 13 | Alabama State (154) | 44 | Final | W | 31 |
| 12 | 2025-11-27 | Tuskegee | Alabama State (154) | Scheduled – 2:00 PM | – | – |