Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2023-09-02 | Fresno State (49) | 39 | Purdue (43) | 35 | Final | L | -4 |
| 2 | 2023-09-09 | Purdue (43) | 24 | Virginia Tech (122) | 17 | Final | W | 7 |
| 3 | 2023-09-16 | Syracuse (15) | 35 | Purdue (70) | 20 | Final | L | -15 |
| 4 | 2023-09-22 | Wisconsin (32) | 38 | Purdue (88) | 17 | Final | L | -21 |
| 5 | 2023-09-30 | Illinois (72) | 19 | Purdue (59) | 44 | Final | W | 25 |
| 6 | 2023-10-07 | Purdue (68) | 14 | Iowa (16) | 20 | Final | L | -6 |
| 7 | 2023-10-14 | Ohio State (6) | 41 | Purdue (75) | 7 | Final | L | -34 |
| 8 | 2023-10-28 | Purdue (83) | 14 | Nebraska (44) | 31 | Final | L | -17 |
| 9 | 2023-11-04 | Purdue (91) | 13 | Michigan (2) | 41 | Final | L | -28 |
| 10 | 2023-11-11 | Minnesota (58) | 30 | Purdue (80) | 49 | Final | W | 19 |
| 11 | 2023-11-18 | Purdue (84) | 15 | Northwestern (60) | 23 | Final | L | -8 |
| 12 | 2023-11-25 | Indiana (100) | 31 | Purdue (78) | 35 | Final | W | 4 |