Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Duquesne (176) | 9 | Pittsburgh (55) | 61 | Final | W | 52 |
| 2 | 2025-09-06 | Central Michigan (122) | 17 | Pittsburgh (55) | 45 | Final | W | 28 |
| 3 | 2025-09-13 | Pittsburgh (55) | 0 | West Virginia (67) | 0 | Scheduled – 3:30 PM | – | – |
| 4 | 2025-09-27 | Louisville (20) | 0 | Pittsburgh (55) | 0 | Scheduled – TBD | – | – |
| 5 | 2025-10-04 | Boston College (51) | 0 | Pittsburgh (55) | 0 | Scheduled – TBD | – | – |
| 6 | 2025-10-11 | Pittsburgh (55) | 0 | Florida State (111) | 0 | Scheduled – TBD | – | – |
| 7 | 2025-10-18 | Pittsburgh (55) | 0 | Syracuse (27) | 0 | Scheduled – TBD | – | – |
| 8 | 2025-10-25 | North Carolina State (83) | 0 | Pittsburgh (55) | 0 | Scheduled – TBD | – | – |
| 9 | 2025-10-31 | Pittsburgh (55) | 0 | Stanford (107) | 0 | Scheduled – TBD | – | – |
| 10 | 2025-11-15 | Notre Dame (3) | 0 | Pittsburgh (55) | 0 | Scheduled – TBD | – | – |
| 11 | 2025-11-22 | Pittsburgh (55) | 0 | Georgia Tech (43) | 0 | Scheduled – TBD | – | – |
| 12 | 2025-11-29 | Miami (15) | 0 | Pittsburgh (55) | 0 | Scheduled – TBD | – | – |