Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Illinois State (139) | 3 | Oklahoma (41) | 35 | Final | W | 32 |
| 2 | 2025-09-06 | Michigan (18) | 13 | Oklahoma (41) | 24 | Final | W | 11 |
| 3 | 2025-09-13 | Oklahoma (41) | 42 | Temple (126) | 3 | Final | W | 39 |
| 4 | 2025-09-20 | Auburn (38) | 17 | Oklahoma (3) | 24 | Final | W | 7 |
| 5 | 2025-10-04 | Kent State (131) | 0 | Oklahoma (6) | 44 | Final | W | 44 |
| 6 | 2025-10-11 | Oklahoma (23) | 6 | Texas (35) | 23 | Final | L | -17 |
| 7 | 2025-10-18 | Oklahoma (16) | 26 | South Carolina (66) | 7 | Final | W | 19 |
| 8 | 2025-10-25 | Ole Miss (8) | 34 | Oklahoma (20) | 26 | Final | L | -8 |
| 9 | 2025-11-01 | Oklahoma (15) | 33 | Tennessee (31) | 27 | Final | W | 6 |
| 10 | 2025-11-15 | Oklahoma (16) | Alabama (5) | Scheduled – 2:30 PM | – | – | ||
| 11 | 2025-11-22 | Missouri (23) | 0 | Oklahoma (41) | 0 | Scheduled – 11:00 AM | – | – |
| 12 | 2025-11-28 | LSU (19) | 0 | Oklahoma (41) | 0 | Scheduled – TBD | – | – |