Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Mississippi State (108) | 34 | Southern Miss (157) | 17 | Final | W | 17 |
| 2 | 2025-09-06 | Arizona State (16) | 20 | Mississippi State (108) | 24 | Final | W | 4 |
| 3 | 2025-09-13 | Alcorn State (215) | 0 | Mississippi State (108) | 0 | Scheduled – 5:00 PM | – | – |
| 4 | 2025-09-20 | Northern Illinois (71) | 0 | Mississippi State (108) | 0 | Scheduled – 3:15 PM | – | – |
| 5 | 2025-09-26 | Tennessee (9) | 0 | Mississippi State (108) | 0 | Scheduled – TBD | – | – |
| 6 | 2025-10-03 | Mississippi State (108) | 0 | Texas A&M (26) | 0 | Scheduled – TBD | – | – |
| 7 | 2025-10-18 | Mississippi State (108) | 0 | Florida (25) | 0 | Scheduled – TBD | – | – |
| 8 | 2025-10-24 | Texas (4) | 0 | Mississippi State (108) | 0 | Scheduled – TBD | – | – |
| 9 | 2025-10-31 | Mississippi State (108) | 0 | Arkansas (46) | 0 | Scheduled – TBD | – | – |
| 10 | 2025-11-08 | Georgia (7) | 0 | Mississippi State (108) | 0 | Scheduled – 11:00 AM | – | – |
| 11 | 2025-11-14 | Mississippi State (108) | 0 | Missouri (23) | 0 | Scheduled – TBD | – | – |
| 12 | 2025-11-28 | Ole Miss (8) | 0 | Mississippi State (108) | 0 | Scheduled – 11:00 AM | – | – |