Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-28 | Stephen F. Austin (163) | 0 | Houston (87) | 27 | Final | W | 27 |
| 2 | 2025-09-06 | Houston (87) | 35 | Rice (101) | 9 | Final | W | 26 |
| 3 | 2025-09-12 | Colorado (35) | 0 | Houston (87) | 0 | Scheduled – 6:30 PM | – | – |
| 4 | 2025-09-26 | Houston (87) | 0 | Oregon State (109) | 0 | Scheduled – 7:30 PM | – | – |
| 5 | 2025-10-03 | Texas Tech (48) | 0 | Houston (87) | 0 | Scheduled – TBD | – | – |
| 6 | 2025-10-10 | Houston (87) | 0 | Oklahoma State (110) | 0 | Scheduled – TBD | – | – |
| 7 | 2025-10-17 | Arizona (102) | 0 | Houston (87) | 0 | Scheduled – TBD | – | – |
| 8 | 2025-10-24 | Houston (87) | 0 | Arizona State (16) | 0 | Scheduled – TBD | – | – |
| 9 | 2025-10-31 | West Virginia (67) | 0 | Houston (87) | 0 | Scheduled – TBD | – | – |
| 10 | 2025-11-07 | Houston (87) | 0 | Central Florida (74) | 0 | Scheduled – TBD | – | – |
| 11 | 2025-11-21 | TCU (39) | 0 | Houston (87) | 0 | Scheduled – TBD | – | – |
| 12 | 2025-11-28 | Houston (87) | 0 | Baylor (38) | 0 | Scheduled – TBD | – | – |