Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-28 | Mississippi Valley State (365) | 61 | 97 | Wyoming (103) | Final | W | 36 |
| 2 | 2020-11-30 | Texas Southern (317) | 76 | 74 | Wyoming (103) | Final | L | -2 |
| 3 | 2020-12-02 | Incarnate Word (280) | 83 | 94 | Wyoming (103) | Final/OT | W | 11 |
| 4 | 2020-12-06 | Wyoming (103) | 76 | 73 | Oregon State (144) | Final | W | 3 |
| 5 | 2020-12-09 | Denver (253) | 61 | 83 | Wyoming (103) | Final | W | 22 |
| 6 | 2020-12-12 | Wyoming (103) | 93 | 88 | Utah Valley (91) | Final | W | 5 |
| 7 | 2020-12-17 | Nebraska-Omaha (272) | 78 | 82 | Wyoming (103) | Final | W | 4 |
| 8 | 2020-12-20 | UNLV (105) | 0 | 0 | Wyoming (103) | Cancelled | - | - |
| 9 | 2020-12-22 | UNLV (105) | 0 | 0 | Wyoming (103) | Postponed | - | - |
| 10 | 2021-01-02 | Wyoming (103) | 78 | 74 | Fresno State (153) | Final | W | 4 |
| 11 | 2021-01-04 | Wyoming (103) | 61 | 81 | Fresno State (153) | Final | L | -20 |
| 12 | 2021-01-11 | Boise State (62) | 83 | 60 | Wyoming (103) | Final | L | -23 |
| 13 | 2021-01-13 | Boise State (62) | 90 | 70 | Wyoming (103) | Final | L | -20 |
| 14 | 2021-01-16 | Wyoming (103) | 69 | 72 | Air Force (347) | Final | L | -3 |
| 15 | 2021-01-18 | Wyoming (103) | 77 | 58 | Air Force (347) | Final | W | 19 |
| 16 | 2021-01-22 | Nevada (67) | 64 | 71 | Wyoming (103) | Final | W | 7 |
| 17 | 2021-01-24 | Nevada (67) | 88 | 93 | Wyoming (103) | Final | W | 5 |
| 18 | 2021-01-28 | Wyoming (103) | 57 | 87 | San Diego State (48) | Final | L | -30 |
| 19 | 2021-01-30 | Wyoming (103) | 71 | 98 | San Diego State (48) | Final | L | -27 |
| 20 | 2021-02-04 | Colorado State (85) | 74 | 72 | Wyoming (103) | Final | L | -2 |
| 21 | 2021-02-06 | Colorado State (85) | 68 | 59 | Wyoming (103) | Final | L | -9 |
| 22 | 2021-02-10 | Wyoming (103) | 0 | 0 | Utah State (25) | Cancelled | - | - |
| 23 | 2021-02-12 | Wyoming (103) | 0 | 0 | Utah State (25) | Postponed | - | - |
| 24 | 2021-02-17 | Wyoming (103) | 83 | 74 | New Mexico (49) | Final/OT | W | 9 |
| 25 | 2021-02-19 | Wyoming (103) | 79 | 67 | New Mexico (49) | Final | W | 12 |
| 26 | 2021-02-25 | San Jose State (229) | 0 | 0 | Wyoming (103) | Cancelled | - | - |
| 27 | 2021-02-27 | San Jose State (229) | 0 | 0 | Wyoming (103) | Cancelled | - | - |
| 28 | 2021-03-04 | Wyoming (103) | 59 | 72 | Utah State (25) | Final | L | -13 |
| 29 | 2021-03-06 | UNLV (105) | 69 | 80 | Wyoming (103) | Final | W | 11 |
| 30 | 2021-03-10 | San Jose State (321) | 80 | 111 | Wyoming (152) | Final | W | 31 |
| 31 | 2021-03-11 | Wyoming (103) | 66 | 69 | San Diego State (48) | Final | L | -3 |