Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-11-13 | Siena (267) | 74 | 92 | Duke (4) | Final | L | -18 |
| 2 | 2015-11-15 | Siena (267) | 65 | 92 | Wisconsin (3) | Final | L | -27 |
| 3 | 2015-11-20 | Siena (267) | 76 | 62 | Radford (162) | Final | W | 14 |
| 4 | 2015-11-21 | Siena (267) | 78 | 59 | Bryant (220) | Final | W | 19 |
| 5 | 2015-11-24 | Siena (267) | 83 | 81 | Bucknell (176) | Final/OT | W | 2 |
| 6 | 2015-11-28 | Loyola-Maryland (284) | 82 | 90 | Siena (267) | Final/OT | W | 8 |
| 7 | 2015-12-01 | Siena (267) | 80 | 81 | Cornell (213) | Final | L | -1 |
| 8 | 2015-12-04 | Manhattan (164) | 54 | 89 | Siena (267) | Final | W | 35 |
| 9 | 2015-12-06 | Siena (267) | 68 | 72 | Saint Peter's (218) | Final | L | -4 |
| 10 | 2015-12-09 | Hofstra (77) | 68 | 81 | Siena (196) | Final | W | 13 |
| 11 | 2015-12-12 | Albany (129) | 70 | 78 | Siena (196) | Final | W | 8 |
| 12 | 2015-12-22 | St. Bonaventure (92) | 70 | 73 | Siena (141) | Final | W | 3 |
| 13 | 2015-12-29 | Siena (120) | 64 | 73 | Vermont (198) | Final | L | -9 |
| 14 | 2016-01-02 | Niagara (291) | 63 | 75 | Siena (120) | Final | W | 12 |
| 15 | 2016-01-04 | Siena (120) | 87 | 92 | Manhattan (282) | Final/3OT | L | -5 |
| 16 | 2016-01-07 | Fairfield (203) | 76 | 91 | Siena (127) | Final | W | 15 |
| 17 | 2016-01-15 | Siena (132) | 64 | 52 | Quinnipiac (282) | Final | W | 12 |
| 18 | 2016-01-18 | Siena (132) | 69 | 85 | Monmouth (66) | Final | L | -16 |
| 19 | 2016-01-21 | Rider (260) | 52 | 63 | Siena (129) | Final | W | 11 |
| 20 | 2016-01-24 | Siena (129) | 99 | 78 | Canisius (204) | Final | W | 21 |
| 21 | 2016-01-26 | Siena (123) | 82 | 70 | Niagara (301) | Final | W | 12 |
| 22 | 2016-01-30 | Marist (311) | 66 | 77 | Siena (123) | Final | W | 11 |
| 23 | 2016-02-01 | Monmouth (71) | 93 | 87 | Siena (123) | Final | L | -6 |
| 24 | 2016-02-05 | Saint Peter's (239) | 52 | 69 | Siena (118) | Final | W | 17 |
| 25 | 2016-02-07 | Siena (118) | 73 | 79 | Marist (314) | Final | L | -6 |
| 26 | 2016-02-11 | Canisius (218) | 67 | 90 | Siena (129) | Final | W | 23 |
| 27 | 2016-02-13 | Siena (129) | 81 | 78 | Iona (149) | Final | W | 3 |
| 28 | 2016-02-19 | Siena (121) | 84 | 64 | Rider (233) | Final | W | 20 |
| 29 | 2016-02-22 | Iona (154) | 87 | 81 | Siena (121) | Final | L | -6 |
| 30 | 2016-02-24 | Siena (117) | 69 | 76 | Fairfield (178) | Final | L | -7 |
| 31 | 2016-02-28 | Quinnipiac (289) | 65 | 80 | Siena (117) | Final | W | 15 |
| 32 | 2016-03-05 | Manhattan (246) | 76 | 89 | Siena (127) | Final | W | 13 |
| 33 | 2016-03-06 | Iona (121) | 81 | 70 | Siena (127) | Final | L | -11 |