Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-11-11 | Penn (197) | 72 | 80 | Fairfield (204) | Final | L | -8 |
| 2 | 2017-11-13 | La Salle (126) | 75 | 71 | Penn (197) | Final/2OT | L | -4 |
| 3 | 2017-11-15 | Navy (214) | 45 | 66 | Penn (197) | Final | W | 21 |
| 4 | 2017-11-18 | Penn State (Brandywine) | 40 | 99 | Penn (197) | Final | W | 59 |
| 5 | 2017-11-20 | Northern Illinois (220) | 80 | 93 | Penn (197) | Final | W | 13 |
| 6 | 2017-11-21 | Towson (147) | 79 | 71 | Penn (178) | Final | L | -8 |
| 7 | 2017-11-22 | Penn (178) | 68 | 65 | UMKC (286) | Final | W | 3 |
| 8 | 2017-11-25 | Penn (178) | 101 | 96 | Monmouth (141) | Final/4OT | W | 5 |
| 9 | 2017-11-29 | Penn (129) | 62 | 90 | Villanova (6) | Final | L | -28 |
| 10 | 2017-12-04 | Penn (129) | 81 | 68 | Howard (345) | Final | W | 13 |
| 11 | 2017-12-06 | Penn (127) | 73 | 68 | Lafayette (320) | Final | W | 5 |
| 12 | 2017-12-09 | Penn (127) | 78 | 70 | Dayton (148) | Final | W | 8 |
| 13 | 2017-12-27 | Delaware State (346) | 52 | 105 | Penn (122) | Final | W | 53 |
| 14 | 2017-12-29 | Toledo (175) | 85 | 72 | Penn (122) | Final | L | -13 |
| 15 | 2018-01-06 | Princeton (153) | 70 | 76 | Penn (146) | Final | W | 6 |
| 16 | 2018-01-12 | Cornell (238) | 61 | 69 | Penn (138) | Final | W | 8 |
| 17 | 2018-01-13 | Columbia (304) | 71 | 77 | Penn (138) | Final | W | 6 |
| 18 | 2018-01-20 | Temple (89) | 60 | 51 | Penn (130) | Final | L | -9 |
| 19 | 2018-01-27 | Saint Joseph's (158) | 56 | 67 | Penn (141) | Final | W | 11 |
| 20 | 2018-02-02 | Brown (235) | 90 | 95 | Penn (130) | Final/OT | W | 5 |
| 21 | 2018-02-03 | Yale (219) | 50 | 59 | Penn (130) | Final | W | 9 |
| 22 | 2018-02-06 | Penn (119) | 82 | 65 | Princeton (165) | Final | W | 17 |
| 23 | 2018-02-09 | Penn (119) | 64 | 61 | Dartmouth (330) | Final | W | 3 |
| 24 | 2018-02-10 | Penn (119) | 67 | 76 | Harvard (215) | Final | L | -9 |
| 25 | 2018-02-16 | Penn (124) | 74 | 62 | Columbia (283) | Final | W | 12 |
| 26 | 2018-02-17 | Penn (124) | 79 | 71 | Cornell (270) | Final | W | 8 |
| 27 | 2018-02-23 | Dartmouth (318) | 46 | 74 | Penn (118) | Final | W | 28 |
| 28 | 2018-02-24 | Harvard (181) | 71 | 74 | Penn (118) | Final | W | 3 |
| 29 | 2018-03-02 | Penn (112) | 79 | 80 | Yale (211) | Final | L | -1 |
| 30 | 2018-03-03 | Penn (112) | 99 | 93 | Brown (271) | Final | W | 6 |
| 31 | 2018-03-10 | Yale (199) | 57 | 80 | Penn (119) | Final | W | 23 |
| 32 | 2018-03-11 | Penn (119) | 68 | 65 | Harvard (174) | Final | W | 3 |