Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-29 | Gannon | 0 | 0 | Niagara (342) | Cancelled | - | - |
| 2 | 2020-12-03 | Niagara (342) | 45 | 75 | Syracuse (84) | Final | L | -30 |
| 3 | 2020-12-11 | Niagara (342) | 54 | 70 | Saint Peter's (200) | Final | L | -16 |
| 4 | 2020-12-12 | Niagara (342) | 49 | 53 | Saint Peter's (200) | Final | L | -4 |
| 5 | 2020-12-18 | Fairfield (204) | 51 | 68 | Niagara (342) | Final | W | 17 |
| 6 | 2020-12-19 | Fairfield (204) | 61 | 81 | Niagara (342) | Final | W | 20 |
| 7 | 2020-12-22 | Niagara (342) | 70 | 65 | Albany (330) | Final | W | 5 |
| 8 | 2021-01-01 | Niagara (342) | 61 | 63 | Marist (178) | Final | L | -2 |
| 9 | 2021-01-02 | Niagara (342) | 86 | 72 | Marist (178) | Final | W | 14 |
| 10 | 2021-01-08 | Rider (356) | 76 | 70 | Niagara (342) | Final | L | -6 |
| 11 | 2021-01-09 | Rider (356) | 55 | 66 | Niagara (342) | Final | W | 11 |
| 12 | 2021-01-15 | Niagara (342) | 49 | 58 | Manhattan (307) | Final | L | -9 |
| 13 | 2021-01-16 | Niagara (342) | 55 | 58 | Manhattan (307) | Final | L | -3 |
| 14 | 2021-01-22 | Niagara | 0 | 0 | Marist | Cancelled | - | - |
| 15 | 2021-01-22 | Niagara (342) | 59 | 56 | Quinnipiac (189) | Final | W | 3 |
| 16 | 2021-01-23 | Niagara | 0 | 0 | Marist | Cancelled | - | - |
| 17 | 2021-01-23 | Niagara (342) | 69 | 78 | Quinnipiac (189) | Final | L | -9 |
| 18 | 2021-01-29 | Monmouth (176) | 77 | 67 | Niagara (342) | Final | L | -10 |
| 19 | 2021-01-30 | Monmouth (176) | 74 | 83 | Niagara (342) | Final | W | 9 |
| 20 | 2021-02-10 | Niagara (342) | 0 | 0 | Iona (220) | Cancelled | - | - |
| 21 | 2021-02-19 | Niagara (230) | 0 | 0 | Iona (182) | Cancelled | - | - |
| 22 | 2021-02-20 | Niagara (230) | 0 | 0 | Iona (182) | Cancelled | - | - |
| 23 | 2021-02-20 | Siena (160) | 62 | 64 | Niagara (342) | Final | W | 2 |
| 24 | 2021-02-21 | Siena (160) | 68 | 66 | Niagara (342) | Final | L | -2 |
| 25 | 2021-02-26 | Canisius (328) | 0 | 0 | Niagara (342) | Cancelled | - | - |
| 26 | 2021-02-27 | Canisius (328) | 0 | 0 | Niagara (342) | Cancelled | - | - |
| 27 | 2021-03-11 | Niagara (342) | 67 | 62 | Marist (178) | Final | W | 5 |
| 28 | 2021-03-12 | Iona (220) | 70 | 64 | Niagara (342) | Final | L | -6 |